Clinical Trials in Massachusetts

Showing 12061-12080 of 15,316 trials

Detecting EGFR T790M Mutations From Circulating Tumor Cells

NCT01734915

The purpose of this research study is to determine if the EGFR mutation can be detected in CTCs. CTCs are cancer cells that are shed from solid tumors and float freely in the bloodstream. A device called the CTC-chip has been developed to find CTCs in the blood of patients with cancer. This is an experimental device. Using this device, the investigators will test participants' blood to try and find CTCs with the EGFR mutation and compare them with the results from the biopsy your doctor has recommended. The long-term goal of this research is to develop a way to test for the EGFR mutation that is less invasive than a tumor biopsy.

Non Small Cell Lung Cancer

Massachusetts General Hospital40 participantsStarted Nov 2012

Boston, Massachusetts, United States • Boston, Massachusetts, United States • New York, New York, United States +1 more locations

COMPLETEDPhase 326 miles

Patients With Epilepsy Taking LAMICTAL Immediate-Release Who Switch To Extended-Release Formulation And Vice Versa

NCT00264615

Pharmacokinetic (PK) study to characterize changes in serum concentrations in epilepsy patients when switching from LAMICTAL immediate-release to extended-release and vice versa.

Epilepsy

GlaxoSmithKline45 participantsStarted Oct 2005

Anniston, Alabama, United States • Sun City, Arizona, United States • Lexington, Kentucky, United States +9 more locations

Detecting EGFR T790M Mutations From Circulating Tumor Cells

Patients With Epilepsy Taking LAMICTAL Immediate-Release Who Switch To Extended-Release Formulation And Vice Versa

Find Trials by Condition in Massachusetts

A Study of RoActemra/Actemra (Tocilizumab) Versus Placebo in Patients With Systemic Sclerosis

Treatment of Multiple Sclerosis With Copaxone and Albuterol

Bevacizumab and BKM-120 in Patients With Metastatic Renal Cell Carcinoma

Study Comparing Weekly Taxol and Carboplatin vs Standard Taxol and Carboplatin Regimen for Stage IIIB or IV Non-Small-Cell Lung Cancer

Sofosbuvir and Ribavirin in Patients With Chronic HCV With Cirrhosis and Portal Hypertension With or Without Liver Decompensation

LUX Lung 2 Phase II Single Arm BIBW 2992 "Afatinib" in NSCLC With EGFR Activating Mutations

Optical Imaging for Preoperative Delineation of Nonmelanoma Skin Cancers

Seasonal Allergic Rhinitis In Pediatric Subjects

A Study to Evaluate the Efficacy of Seasonique for the Treatment of Cyclic Pelvic Pain

The Effect of Neoadjuvant DMPA on Glandular Cellularity in Women Awaiting Hysterectomy

Rosiglitazone In Subjects With Type 2 Diabetes Mellitus Who Are Inadequately Controlled On Insulin

Efficacy of 851B Gel for Treating High-Risk Cervical Human Papillomavirus Infection in Women.

Human Fibrinogen - Pharmacokinetics

Coronary Artery Bypass Surgery (CABG) Off or On Pump Revascularization Study

Finding a Safe and Effective Dose of Linagliptin in Pediatric Patients With Type 2 Diabetes

Study to Compare Safety and Immunogenicity of Commercial Scale Consistency Lots of Herpes Simplex Vaccine

A Prospective Trial to Identify Biomarkers Involved in the Transition From Acute to Persistent Chronic Low Back Pain

Treatment Of Impetigo With Topical SB-275833 Ointment, 1% Versus Topical Placebo Ointment