Clinical Trials in Massachusetts

Showing 10921-10940 of 15,316 trials

Study of INCB039110 in Combination With Docetaxel in Subjects With Non-Small Cell Lung Cancer

NCT02257619

The primary objectives of this study is to evaluate the safety and tolerability of itacitinib in combination with docetaxel and to select doses for further evaluation (Part 1, safety run-in portion).

NSCLC (Non-small Cell Lung Carcinoma)

Incyte Corporation9 participantsStarted Sep 2014

Hot Springs, Arizona, United States • Los Angeles, California, United States • Washington D.C., District of Columbia, United States +13 more locations

COMPLETEDPhase 226 miles

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Followed by Radiation Therapy and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery

NCT00553462

RATIONALE: Drugs used in chemotherapy, such as carboplatin and paclitaxel albumin-stabilized nanoparticle formulation, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Radiation therapy uses high-energy x-rays to kill tumor cells. Erlotinib may make tumor cells more sensitive to radiation therapy. Giving carboplatin and paclitaxel albumin-stabilized nanoparticle formulation together with radiation therapy and erlotinib may kill more tumor cells. PURPOSE: This phase II trial is studying how well giving carboplatin and paclitaxel albumin-stabilized nanoparticle formulation together with radiation therapy and erlotinib works in treating patients with stage III non-small cell lung cancer that cannot be removed by surgery.

Lung Cancer

Alliance for Clinical Trials in Oncology78 participantsStarted Mar 2008

Castro Valley, California, United States • Castro Valley, California, United States • Fremont, California, United States +96 more locations

Study of INCB039110 in Combination With Docetaxel in Subjects With Non-Small Cell Lung Cancer

Carboplatin and Paclitaxel Albumin-Stabilized Nanoparticle Formulation Followed by Radiation Therapy and Erlotinib in Treating Patients With Stage III Non-Small Cell Lung Cancer That Cannot Be Removed By Surgery

Find Trials by Condition in Massachusetts

A Study to Investigate Mepolizumab in the Treatment of Eosinophilic Granulomatosis With Polyangiitis

Biopsies of Cancer Patients for Tumor Molecular Characterization

Cardiopulmonary Rehabilitation for Adolescents and Adults With Congenital Heart Disease

Effectiveness of Aurix Therapy in Pressure Ulcers

Does 3D Laparoscopy Improve Vaginal Cuff Suture Time?

Systems of Support Study for Childhood Depression

NOLAN: Naproxen or Loratadine and Neulasta

Study of Daptomycin in Subjects Undergoing Surgery for Osteomyelitis Associated With an Infected Prosthetic Caused by Staphylococci

Safety and Tolerability Study of an Edible Colon Preparation

A Randomized, Multi-center, Open-label, Paired Controlled, Crossover In Vivo Study

Asthma Exacerbation Study

Lesinurad and Febuxostat Combination Extension Study in Gout

Evaluate the Efficacy and Safety of Arhalofenate for Preventing Flares and Reducing Serum Uric Acid in Gout Patients

Uninterrupted Dabigatran Etexilate in Comparison to Uninterrupted Warfarin in Pulmonary Vein Ablation (RE-CIRCUIT)

A 24-week Evaluation of GSK573719/Vilanterol (125/25mcg) and Components in COPD

Efficacy and Safety of the Addition of Fluticanse Propionate/Salmeterol (250/50mcg) Twice-daily to 2 Doses of Umeclidinium Bromide (62.5 or 125mcg) Once-daily Over 12 Weeks

Extension Study of Drisapersen in DMD Subjects

Unrecognised Obstructive Sleep Apnea Study