Clinical Trials in Massachusetts

Showing 8761-8780 of 13,570 trials

Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages

NCT02856776

There continues to be debate as to how much vitamin D an adult requires to be vitamin D sufficient. A multitude of association studies have suggested that improving serum 25(OH)D \>30 ng/mL may reduce risk of many chronic illnesses and improve immune function. The aim of this study is to define dynamic changes in PTH, broad gene expression in circulating immune cells, metabolomics, and microbiome profile in response to varying doses of vitamin D supplementation.

Vitamin D Insufficiency

Boston University39 participantsStarted Dec 2017

Boston, Massachusetts, United States

WITHDRAWNPhase 426 miles

The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis

NCT03363789

The purpose of this study is to compare the effectiveness of ultrasound guided brisement, brisement without ultrasound guidance and standard conservative treatment in patients who have been diagnosed with Achilles tendinosis. We are asking you to take part in this research study because you are a patient of the Brigham Foot and Ankle Clinic who has been diagnosed with Achilles tendinosis. About 100 people will take part in this research study, all at Brigham and Women's Hospital (BWH). To our knowledge, there has been very little research in the efficacy of the addition of briesment injections to standard, conservative treatment of Achilles tendinosis. We hope our results will show which method is the most effective conservative treatment for Achilles tendinosis. This information will help doctors make decisions in the future.

Achilles Tendinopathy

Brigham and Women's HospitalStarted Feb 2018

Boston, Massachusetts, United States

COMPLETEDPhase 2/326 miles

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

NCT01737398

The purpose of this study is to evaluate the efficacy and safety of inotersen given for 65 weeks in participants with Familial Amyloid Polyneuropathy (FAP).

FAPFamilial Amyloid PolyneuropathyTTR+2 more

Ionis Pharmaceuticals, Inc.173 participantsStarted Mar 2013

Orange, California, United States • Indianapolis, Indiana, United States • Baltimore, Maryland, United States +21 more locations

Gene Expression, Metabolomic, Microbiome, and Calcium Metabolism in Response to Varied Vitamin D Dosages

The Efficacy of Brisement Compared to Physical Therapy for the Treatment of Achilles Tendinosis

Efficacy and Safety of Inotersen in Familial Amyloid Polyneuropathy

Find Trials by Condition in Massachusetts

IText For ICOUGH: Improving Ambulation of Surgical Patients Through Text Messaging

Registry for Integrative Medicine Interventions Effectiveness

Patient Safety Learning Laboratory: Making Acute Care More Patient-Centered

Effects of Cognitive and Emotional Functioning on Treatment Outcomes

Stress, Distress Intolerance, and Drug Dependence

Paclitaxel, Cisplatin, and Veliparib in Treating Patients With Advanced, Persistent, or Recurrent Cervical Cancer

Fetal ST Segment and T Wave Analysis in Labor

Omega-3 Fatty Acid Supplementation to Prevent Preterm Birth in High Risk Pregnancies

Magnetic Resonance Imaging in Women Recently Diagnosed With Unilateral Breast Cancer

Standard Dose Versus High Dose and Versus Extended Standard Dose Radium-223 Dichloride in Castration-resistant Prostate Cancer Metastatic to the Bone

Head-to-Head Study of Etelcalcetide (AMG 416) and Cinacalcet

Study to Assess the Injection Site Pain Associated With a New Etanercept Formulation in Adults With Rheumatoid Arthritis or Psoriatic Arthritis

Efficacy and Safety Study of Idelalisib in Participants With Indolent B-Cell Non-Hodgkin Lymphomas

Expanded Treatment Protocol (ETP) of Ruxolitinib in Patients With Polycythemia Vera Who Were Hydroxyurea Resistant or Intolerant and for Whom no Treatment Alternatives Was Available.

A Single-dose Study in Paediatric Patients Aged 2 to Less Than 18 Years With Secondary Hyperparathyroidism (sHPT) Receiving Haemodialysis

Sevuparin Infusion for the Management of Acute VOC in Subjects With SCD

Comparative Study of Fluticasone Furoate(FF)/Umeclidinium Bromide (UMEC)/ Vilanterol (VI) Closed Therapy Versus FF/VI Plus UMEC Open Therapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)