Clinical Trials in Massachusetts

Showing 7621-7640 of 13,570 trials

Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression

NCT03999736

This is an add-on study to an existing multimodal neuroimaging study in MDD by investigating the acute effects of DLPFC tDCS on threat vigilance in 24-44 patients with MDD, as part of an open-label treatment intervention study. Behavioral and neural measures of threat vigilance will be taken acutely and investigated as predictors of subsequent treatment response to a four-week, fourteen-session DLPFC tDCS intervention, using a novel home-tDCS protocol. The design takes advantage of an existing rich set of candidate baseline behavioral, neural and molecular measures from the existing neuroimaging study, which could be used to predict treatment response to tDCS and thereby, aid future patient selection for clinical trials.

Major Depressive DisorderAnxiety

Mclean Hospital1 participantsStarted Feb 2020

Belmont, Massachusetts, United States

TERMINATEDNA25 miles

MINDFUL-PC for Portuguese Speakers Pilot Study 2020

NCT04268355

The study evaluates the effects of the Mindfulness Training for Primary Care (MTPC) Portuguese-adapted version on heart rate variability during a demanding cognitive task. The study also evaluates the effects on mental health, quality of life, self-regulation and behavior outcomes. The study will also complete the MTPC cultural adaptation process for Brazilian culture.

DepressionAnxiety DisordersStress Related Disorder+2 more

Cambridge Health Alliance15 participantsStarted Jan 2020

Somerville, Massachusetts, United States

Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression

MINDFUL-PC for Portuguese Speakers Pilot Study 2020

Find Trials by Condition in Massachusetts

Betadine Effect on Nasal Mucosa Cilia

Phase 2 Study of Bevacizumab in Children and Young Adults With NF 2 and Progressive Vestibular Schwannomas

Randomized Trial to Assess PO Versus IV Antibiotics

Alcohol and Sex Risk Intervention for MSM Supplement

Study of MEDI4736 Monotherapy and in Combination With Tremelimumab Versus Standard of Care Therapy in Patients With Head and Neck Cancer

Safety of Rivipansel (GMI-1070) in the Treatment of One or More Vaso-Occlusive Crises in Hospitalized Subjects With Sickle Cell Disease

The ICON Study: Outcomes After FMT for Patients With IBD and CDI

Comparative Study of Intermittent Catheters and Occurrence of Urinary Tract Infections

Pregabalin in the Treatment of Patients With Generalized Anxiety Disorder (GAD).

A Multi-Risk Factor Strategy vs a Guideline-Based Approach in Achieving Blood Pressure and Lipid Goals in Hypertensives at Extra Risk

Study to Evaluate Efficacy and Safety of E-101 Solution for Preventing Surgical Site Infections After Colorectal Surgery

The Altis® Single Incision Sling System for Female Stress Urinary Incontinence Study

A-Health RCT: Effects of Participatory Art-based Activity on Health of Older Community Dwellers

Lyrica Dose Response Study With Restless Legs Syndrome (RLS) Patients

Safety, Tolerability, and Pharmacokinetic Study of Pregabalin in Pediatric Patients With Partial Onset Seizures

P4 (Pregabalin for Peripheral Posttraumatic Pain)

Efficacy and Safety of Pregabalin vs Placebo for Generalized Anxiety Disorder (GAD) Symptoms in Subjects Discontinuing Benzodiazepine Treatment and Remaining 6 Weeks on Study Medication, Free From Benzodiazepine Use.

Safety, Tolerability and Efficacy of Rapid Optimization, Helped by NT-proBNP testinG, of Heart Failure Therapies