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Clinical TrialsMassachusetts

Clinical Trials in Massachusetts

Discover 27,577 clinical trials near Massachusetts. Find research studies in your area.

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma Pancreatic Cancer

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 741-760 of 27,577 trials

CompletedChemotherapy and Radiation Therapy in Treating Patients With Locally Advanced Pancreatic CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00049348·Scottsdale, Arizona and 136 others

Find Trials by Condition in Massachusetts

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Data from ClinicalTrials.govTerms

RecruitingBOLSTER: Learning New Skills to ThriveThis research study is evaluating a new program called Building Out Lifelines for Safety, Trust, Empowerment, and Renewal or (BOLSTER), which was designed to support participants…NCT06936878·Boston, Massachusetts and 1 other

RecruitingContinuous Glucose Monitor Use in PregnancyThe purpose of this study is to perform a randomized controlled trial among 180 pregnant women with type 2 diabetes mellitus (T2DM) comparing continuous glucose monitor (CGM) use…NCT05317585·Worcester, Massachusetts

CompletedDeepView SnapShot Portable (DV-SSP): Device Training StudyThe purpose of this study is to continue development and validation of an algorithm for burn healing assessment by the Spectral MD DeepView device and provide burn healing…NCT05023135·Birmingham, Alabama and 10 others

CompletedSNAP Fruit and Vegetable Incentive Program Digital Promotions for Farmers' MarketsThe purpose of this study is to assess the impact of digital promotions of a Supplemental Nutrition Assistance Program (SNAP) fruit and vegetable incentive program on SNAP…NCT04458350·Boston, Massachusetts

CompletedCombination Chemotherapy, Radiation Therapy and Surgery for Esophageal CancerThe purpose of this study is to find out what effects (good and bad) the combination of three chemotherapy drugs (cetuximab, cisplatin, and irinotecan) have on esophageal cancer…NCT00165490·Boston, Massachusetts and 1 other

RecruitingDemonsTTRate: A Global, Observational, Multicenter, Long-term Study of Patients With ATTR-CM in a Real-World SettingThe purpose of this study is to: * Describe the clinical characteristics of adult patients with transthyretin-mediated amyloidosis with cardiomyopathy (ATTR-CM) treated with…NCT07358078·Tucson, Arizona and 26 others

CompletedA Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-01)This study will evaluate the efficacy, safety, and tolerability of rapastinel 450 mg compared to placebo adjunctive to antidepressant therapy (ADT) in patients with major…NCT02932943·Beverly Hills, California and 30 others

CompletedMelatonin Supplements for Improving Sleep in Individuals With HypertensionThis study will evaluate the effectiveness of treatment with melatonin supplements in improving sleep in individuals with high blood pressure who are taking beta-blockers.NCT00238108·Boston, Massachusetts

CompletedA Safety Study of Rituximab Plus MTX Injected Into the Cerebrospinal Fluid in the Treatment of Brain LymphomaRituximab is the first monoclonal antibody to receive approval in the treatment of cancer and has been proven to lead to extended survival when administered intravenously in the…NCT00221325·San Francisco, California and 3 others

RecruitingPK, Safety and Preliminary Efficacy Study of Montelukast in Critically Ill Infants With Developing Bronchopulmonary DysplasiaThe purpose of the study is to learn how safe montelukast may be in premature infants at significant risk for Bronchopulmonary Dysplasia (BPD) and to determine how much and how…NCT07101640·Little Rock, Arkansas and 4 others

CompletedA Study of Fresolimumab in Patients With Steroid-Resistant Primary Focal Segmental Glomerulosclerosis (FSGS)The primary objectives of this trial are as follows: * to compare the achievement of a partial remission (PR) or complete remission (CR) in urinary protein: creatinine ratio…NCT01665391·Birmingham, Alabama and 31 others

CompletedStudy to Evaluate the Safety, Tolerability and the Effect of BMS-241027 on Cerebrospinal Fluid Biomarkers in Subjects With Mild Alzheimer's DiseaseThe purpose of the study is to evaluate safety and the pharmacodynamic effects of BMS-241027 on cerebrospinal fluid (CSF) Tau, connectivity magnetic resonance imaging (MRI), and…NCT01492374·Anaheim, California and 23 others

TerminatedA Study of E7050 in Combination With E7080 in Participants With Advanced Solid Tumors (Dose Escalation) and in Participants With Recurrent Glioblastoma or Unresectable Stage III or Stage IV Melanoma After Prior Systemic Therapy (Expansion Cohort and Phase 2)This is a multicenter, open-label, Phase 1b/2 study which will be conducted in two parts: a Phase 1b part comprising a dose escalation and an expansion cohort; and a Phase 2 part…NCT01433991·Boston, Massachusetts and 1 other

TerminatedStudy of Disease Progression in Adults With Inherited Forms of Spastic ParaplegiaThe course of AMN-related disabilities over time is poorly or incompletely understood due to a limited number of patients and lack of treatments.NCT05008874·Stanford, California and 5 others

TerminatedPrevention of Recurrence of Crohn's Disease by Fecal Microbiota Therapy (FMT)The objective of this trial is to assess if Fecal Microbiota Therapy (FMT) can reduce the risk of endoscopic recurrence of Crohn's disease (CD) in patients after intestinal…NCT02417974·Boston, Massachusetts and 1 other

CompletedRussia PREVENT (HIV Prevention Partnership in Russian Alcohol Treatment)The purpose of this study is to test an HIV prevention intervention in a Russian substance abuse treatment facility using a randomized trial study design.NCT00183118·Boston, Massachusetts

TerminatedSafety Study for the Treatment of Abdominal Aortic AneurysmsThe primary study objective, at this time, is to follow out to 5 years post implant the safety of already enrolled subjects who were treated with the UniFit Aorto-uni-iliac (AUI)…NCT00610090·Loma Linda, California and 18 others

WithdrawnSystemic Rapamycin (Sirolimus) to Prevent In-Stent Restenosis Following Pulmonary Artery Stent PlacementThis is a research study to assess whether an oral medication can benefit some patients being treated for peripheral pulmonary stenosis (PPS), which is narrowing of the blood…NCT02365415·Boston, Massachusetts

Active not recruitingLeucovorin for the Treatment of Language Impairment in Children With Autism Spectrum DisorderThe purpose of this study is to determine the effectiveness of folinic acid in the treatment of language problems in children with autism spectrum disorder.NCT02839915·Phoenix, Arizona and 3 others

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