Clinical Trials in Massachusetts

Showing 5721-5740 of 17,868 trials

Feasibility Study of Intraoperative Detection of Residual Cancer in Breast Cancer Patients

NCT04440982

This is a prospective, multi-center, randomized, clinical trial evaluating patients undergoing breast conserving surgery using the LUM Imaging System.

Breast CancerNeoadjuvant Therapy

Lumicell, Inc.98 participantsStarted Sep 2020

Palo Alto, California, United States • Clearwater, Florida, United States • Boston, Massachusetts, United States +3 more locations

RECRUITINGPhase 426 miles

Evaluating Treatment of ADHD in Children with Down Syndrome

NCT04219280

Children with Down syndrome (DS) have a 3-5 time greater prevalence of Attention Deficit Hyperactivity Disorder (ADHD) than typically developing (TD) children. Despite this higher risk of ADHD, rates of stimulant medication treatment are disproportionately low in children with DS+ADHD, even though stimulants are the most efficacious ADHD treatment and are recommended by consensus guidelines for use in children with intellectual disability and ADHD. The investigators propose the first randomized clinical trial (RCT) of stimulant medication in children with DS+ADHD. This RCT may provide evidence regarding the short- and long-term safety and efficacy of stimulant use in children with DS+ADHD, both with and without CHD. All children enrolled in the study will complete a comprehensive assessment battery evaluating ADHD diagnostic criteria, as well as behavioral, cognitive, academic, and functional impairments.

Down SyndromeADHD

Children's Hospital Medical Center, Cincinnati100 participantsStarted Oct 2020

Sacramento, California, United States • Boston, Massachusetts, United States • Cincinnati, Ohio, United States +1 more locations

Feasibility Study of Intraoperative Detection of Residual Cancer in Breast Cancer Patients

Evaluating Treatment of ADHD in Children with Down Syndrome

Find Trials by Condition in Massachusetts

Improving Treatment and Retention Adherence in Nontraditional Settings

PERSEVERE- A Trial to Evaluate AMDS in Acute DeBakey Type I Dissection

Feasibility of the LUM Imaging System for Detection of Cancer to the Brain

Limbal Stem Cell Deficiency (LSCD) Treatment With Cultivated Stem Cell (CALEC) Graft

Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection

Community Interventions in Non-medical Settings to Increase Informed Decision Making for Prostate Cancer Screening

A Study of the Safety of Oral Elsubrutinib Capsules and Oral Upadacitinib Tablets Given Alone or in Combination (ABBV-599) for Adult Participants With Moderately to Severely Active Systemic Lupus Erythematosus to Assess Change in Disease State

Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies

Nemaline Myopathy Clinical Research Network (NM-CTRN)

Rapid Evaluation of Innovative Intervention Components to Maximize the Health Benefits of Behavioral Obesity Treatment Delivered Online: An Application of Multiphase Optimization Strategy

Individual and Family Motivational Interviews for Substance Using Truant Teens

Electronic Patient Reporting of Symptoms During Cancer Treatment

Lifestyle Intervention for Young Adults With Serious Mental Illness

Study to Assess the Efficacy and Safety of NBI-1065845 in Adults With Major Depressive Disorder (MDD)

Open-Label Study With Pimavanserin on Activities of Daily Living in Subjects With Parkinson's Disease Psychosis

Safety, Tolerability, and Pharmacokinetics of Clesrovimab (MK-1654) in Infants (MK-1654-002)

Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors

Posaconazole (MK-5592) Intravenous and Oral in Children With Invasive Aspergillosis (IA) (MK-5592-104)