Clinical Trials in Massachusetts

Showing 4961-4980 of 17,868 trials

Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia

NCT06174116

The main question this study is trying to answer is whether lumateperone, an FDA-approved antipsychotic drug, can help reduce possible side effects of clozapine, such as weight gain and elevated levels of sugar and bad cholesterol. Participants will be randomly assigned to either take lumateperone (Caplyta) or a placebo for 12 weeks, in addition to their regularly prescribed clozapine. During their participation, patients will answer questions about their psychiatric and daily functioning, have blood drawn, and have their body composition analyzed (similar to stepping on a scale).

SchizophreniaSchizo Affective Disorder

University of Massachusetts, Worcester50 participantsStarted Apr 2024

Worcester, Massachusetts, United States

RECRUITING26 miles

Parkinson's Foundation PD GENEration Genetic Registry

NCT04994015

Development of a central repository for PD-related genomic data for future research.

Parkinson's Disease

Parkinson's Foundation25,000 participantsStarted Dec 2020

Birmingham, Alabama, United States • Chandler, Arizona, United States • Phoenix, Arizona, United States +53 more locations

Metabolic Effects of Adjunctive Lumateperone Treatment in Clozapine-Treated Patients With Schizophrenia

Parkinson's Foundation PD GENEration Genetic Registry

Find Trials by Condition in Massachusetts

Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)

Efficacy, Safety and Pharmacokinetics of Rilzabrutinib in Patients With Warm Autoimmune Hemolytic Anemia (wAIHA)

A Registry for People With T-cell Lymphoma

NUDGE-EHR Replication Trial at Mass General Brigham

Safety, Tolerability and Acceptability of Long-Acting Cabotegravir (CAB LA) for the Prevention of HIV Among Adolescent Males

Tools for Reducing Inequity in Acute Leukemia (TRIAL): Beta Testing

SURPASS Impella 5.5 Study

BCMA-directed CAR-T Cell Therapy in Adult Patients With Multiple Myeloma

An Informational and Supportive Care Intervention for Patients With Locally Advanced Rectal Cancer

A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease

Phase 1b Trial of RAY121 in Immunological Diseases (RAINBOW Trial)

Early Feasibility Study of the Neovasc Tiara™ Mitral Valve System

Efficacy & Safety of rAd-IFN Administered With Celecoxib & Gemcitabine in Patients With Malignant Pleural Mesothelioma

Stopping Aminosalicylate Therapy in Inactive Crohn's Disease

RecruitmEnt Assessed by eleCtRical Impedance Tomography

A Retrospective Chart Review Study of Patients With Chronic Lung Allograft Dysfunction-Bronchiolitis Obliterans Syndrome (CLAD-BOS) Post Lung Transplantation

DiEtary Sodium Intake Effects on Ertugliflozin-induced Changes in GFR, reNal Oxygenation and Systemic Hemodynamics: the DESIGN Study, a Randomized, Placebo-controlled, Cross-over Study With Ertugliflozin in People With Type 2 Diabetes

Digital Support Systems to Improve Child Health and Development in Peru