Clinical Trials in Massachusetts

Showing 3321-3340 of 15,316 trials

Tolerance Through Mixed Chimerism (Sip-Tego)

NCT06972069

This is an open-label, single-institution study to assess the safety and the efficacy of the Sip-Tego regimen for the induction of donor-specific immunologic unresponsiveness to a renal allograft. The investigators propose to treat 6 adult subjects in end-stage renal disease (ESRD) who do not demonstrate evidence of prior sensitization.

Kidney FailureTransplant Recipient (Kidney)Transplant Tolerance+2 more

Tatsuo Kawai, MD, PhD12 participantsStarted May 2025

Boston, Massachusetts, United States

COMPLETEDPhase 226 miles

ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder

NCT05749055

The ENCALM trial is designed to evaluate the efficacy and safety of ENX-102 in patients diagnosed with generalized anxiety disorder (GAD)

Generalized Anxiety Disorder

Engrail Therapeutics INC252 participantsStarted Jul 2023

Phoenix, Arizona, United States • Garden Grove, California, United States • Imperial, California, United States +29 more locations

Tolerance Through Mixed Chimerism (Sip-Tego)

ENCALM: A Study of ENX-102 as a Monotherapy Treatment in Patients With Generalized Anxiety Disorder

Find Trials by Condition in Massachusetts

Testing the Efficacy of Topical Calcipotriene Plus 5-Fluorouracil Combination to Activate the Immune System Against Precancerous Skin Lesions in Organ Transplant Recipients

A Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)

Phase 2a Study of VX-147 in Adults With APOL1-mediated Focal Segmental Glomerulosclerosis

Comparing Hypothermic Temperatures During Hemiarch Surgery

A Study Evaluating the Long-term Safety and Efficacy of VX-445 Combination Therapy

Brentuximab Vedotin and Nivolumab for the Treatment of Patients With Relapsed/Refractory Classical Hodgkin Lymphoma

Computerized Registry of Patients With Venous Thromboembolism (RIETE)

A Study Testing the Use of a Perivascular Sirolimus Formulation (Sirogen) in ESRD Patients Undergoing AV Fistula Surgery

Study to Evaluate Safety and Efficacy of VX-661 in Combination With Ivacaftor in Subjects With Cystic Fibrosis, Homozygous for the F508del-CFTR Mutation With an Open-Label Expansion

Hydroxychloroquine in Outpatient Adults With COVID-19

A Study to Investigate the Safety of DSP-3077 After a Unilateral Eye Injection in Male and Female Participants 18 Years of Age or Older With Retinitis Pigmentosa

CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

A Clinical Trial on Safety and Efficacy of CBT-001 in Patients With Pterygium

A Study to Evaluate ELX/TEZ/IVA on Cough and Physical Activity in Participants With Cystic Fibrosis (CF)

Phase 2 Safety and Efficacy Evaluation of AL8326 in ≥2nd Line SCLC

Phase1/2a Study for IPG7236 in Patients With Advanced Solid Tumors