Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
William Stevenson
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Monomorphic ventricular tachycardia (VT) or incessant ventricular arrhythmia (defined as \>20% of beats due to ventricular arrhythmia including unifocal premature ventricular contractions (PVCs ), couplets, nonsustained VT) that is causing a decline in left ventricular (LV) ejection fraction to less than 0.50.
Arrhythmia meets the following criteria:
1. Ventricular arrhythmia is recurrent and symptomatic
2. prior antiarrhythmic drug therapy has failed due to recurrent ventricular arrhythmia, toxicity, or intolerance
* Age 18 or older
* Left ventricular (LV) ejection fraction \> 0.10 as estimated by echocardiography or contrast ventriculography within the previous 90 days
* Failed prior VT or PVC ablation due to spontaneous recurrence of the arrhythmia or frequent PVCs.
* Able and willing to comply with all pre-, post-, and follow-up testing and requirements
* Signed Informed Consent
You may not be if
Patients with idiopathic VT defined as VT that originates from a region without evidence of scar detected by MRI or voltage mapping in a patient without other evidence of heart disease that is not causing significant depression of ventricular function.
Definite protruding left ventricular thrombus on pre-ablation echocardiography when LV ablation is required.
Thrombotic myocardial infarction within the preceding two (2) months.
Other disease process that is likely to limit survival to less than 12 months.
Class IV heart failure, unless heart failure is due to frequent or incessant VT.
Contraindication to heparin.
Allergy to radiographic contrast dye.
Severe aortic stenosis
Severe mitral regurgitation with a flail mitral valve leaflet.
Significant congenital anomaly or medical problem that in the opinion of the principal investigator would preclude enrollment into the study.
Enrolled in another investigational study evaluating a drug or device.
Unstable angina that is not due to frequent or incessant VT.
Women who are pregnant.
Thrombocytopenia (platelet count \< 50,000) or coagulopathy.
Acute non-cardiovascular illness or systemic infection.
Cardiogenic shock unless it is due to incessant VT
