Clinical Trials in Massachusetts

Showing 3201-3220 of 15,316 trials

The IDEA Study (Individualized Decisions for Endocrine Therapy Alone)

NCT02400190

This study will collect rates of local/regional recurrence in select patients who do not receive radiation treatment after lumpectomy surgery. These women must be postmenopausal; have hormone receptor-positive, Her2-negative tumors; have Oncotype-DX RS less than or equal to 18; and plan to receive endocrine therapy. In this way, this study seeks to collect prospective data supporting the idea that this is a population at sufficiently low risk of local/regional recurrence that omission of adjuvant radiation might be a reasonable option.

Breast Neoplasms

University of Michigan Rogel Cancer Center202 participantsStarted May 2015

Stanford, California, United States • New Haven, Connecticut, United States • Maywood, Illinois, United States +10 more locations

TERMINATEDPhase 226 miles

A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens

NCT05370521

An investigation of the safety and efficacy of tildacerfont in women with PCOS and elevated adrenal androgens

Polycystic Ovary Syndrome

Spruce Biosciences27 participantsStarted May 2022

Sacramento, California, United States • San Francisco, California, United States • New Haven, Connecticut, United States +18 more locations

The IDEA Study (Individualized Decisions for Endocrine Therapy Alone)

A Study of Safety and Efficacy of Tildacerfont in Females With Polycystic Ovary Syndrome and Elevated Adrenal Androgens

Find Trials by Condition in Massachusetts

Neuropsychological and Mental Outcomes of Operation Iraqi Freedom (OIF): A Longitudinal Cohort Study

Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer

A Phase 1/2 Study of CPI-0610 With and Without Ruxolitinib in Patients With Hematologic and Myeloproliferative Malignancies

A Study of Xevinapant (Debio 1143) in Combination With Platinum-Based Chemotherapy and Standard Fractionation Intensity-Modulated Radiotherapy in Participants With Locally Advanced Squamous Cell Carcinoma of the Head and Neck, Suitable for Definitive Chemoradiotherapy (TrilynX)

High-flow Nasal Oxygen Therapy for Advanced Endoscopy in High-risk Patients.

Study of Relacorilant in Combination With Nab-Paclitaxel for Patients With Recurrent Platinum-Resistant Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Fractionated Docetaxel and Radium 223 in Metastatic Castration-Resistant Prostate Cancer

Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

A Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of SPR720 as Compared With Placebo for the Treatment of Participants With Mycobacterium Avium Complex (MAC) Pulmonary Disease

SPI-62 as a Treatment for Adrenocorticotropic Hormone-dependent Cushing's Syndrome

Open-label Extension Study of Enlicitide Decanoate (MK-0616/Enlicitide Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-019) CORALreef Extension

Partial Breast Re-irradiation Using Ultra Hypofractionation (PRESERVE)

Efficacy, Safety, and Tolerability of LPRI-CF113 as an Oral Contraceptive in Females

Frespaciguat (MK-5475) INSIGNIA-PH-COPD: A Study of the Efficacy and Safety of Frespaciguat (an Inhaled sGC Stimulator) in Adults With PH-COPD

Efficacy and Safety of Tisagenlecleucel in Adult Patients With Refractory or Relapsed Follicular Lymphoma

Dose Ranging Study of Amlitelimab in Adult Participants With Moderate-to-severe Asthma

Efficacy of KL1333 in Adult Patients With Primary Mitochondrial Disease