Clinical Trials in Massachusetts

Showing 2921-2940 of 8,511 trials

Study of the Associations Between Subchondral Insufficiency Fractures of the Knee and Pre-existing Health, Lifestyle, and/or Musculoskeletal Conditions

NCT04953702

This prospective cohort study is designed to investigate possible association(s) between subchondral insufficiency fractures (SIFKs) of the knee and pre-existing health, lifestyle, and/or musculoskeletal conditions. In doing so, this research may shed light on the underlying cause(s) of SIFKs. It is hypothesized that SIFKs of the knee are related to osteoarthritis, weak bone, and/or metabolic issues, rather than trauma.

Subchondral Insufficiency Fracture

University of Massachusetts, WorcesterStarted Jun 2021

Worcester, Massachusetts, United States

TERMINATEDPhase 326 miles

Open-Label Extension Study of Trofinetide for Rett Syndrome

NCT04776746

To investigate the safety and tolerability of continued long-term treatment with oral trofinetide in girls and women with Rett syndrome

Rett Syndrome

ACADIA Pharmaceuticals Inc.77 participantsStarted Nov 2020

Birmingham, Alabama, United States • Phoenix, Arizona, United States • La Jolla, California, United States +18 more locations

Study of the Associations Between Subchondral Insufficiency Fractures of the Knee and Pre-existing Health, Lifestyle, and/or Musculoskeletal Conditions

Open-Label Extension Study of Trofinetide for Rett Syndrome

Find Trials by Condition in Massachusetts

LED Treatment to Improve Cognition and Promote Recovery in TBI

A Study of Semorinemab in Patients With Moderate Alzheimer's Disease

HIV Exposure in Utero and Metabolic Disease Risk in HIV-Negative Young Adults

Immunotherapy With IFx-Hu2.0 Vaccine for Advanced Non-melanoma Skin Cancers

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients

Long-term Safety of Lumacaftor/Ivacaftor in Participants With Cystic Fibrosis Who Are Homozygous for F508del and 12 to <24 Months of Age at Treatment Initiation

A Study of Sotatercept for the Treatment of Pulmonary Arterial Hypertension (MK-7962-003/A011-11)(STELLAR)

Pembrolizumab and Reirradiation in Bevacizumab Naïve and Bevacizumab Resistant Recurrent Glioblastoma

Phase 1, First-in-human Study of Oral TP-1287 in Patients with Advanced Solid Tumors

The PREDICT Registry:

Zephyrus I: Evaluation of Efficacy and Safety of Pamrevlumab in Participants With Idiopathic Pulmonary Fibrosis (IPF)

A Study on the Immune Response and Safety Elicited by a Vaccine Against Respiratory Syncytial Virus (RSV) When Given Alone and Together With a Vaccine Against Influenza in Adults Aged 65 Years and Above

S1314, Co-expression Extrapolation (COXEN) Program to Predict Chemotherapy Response in Patients With Bladder Cancer

Extension Study of Patidegib Topical Gel, 2% in Subjects With Gorlin Syndrome (Basal Cell Nevus Syndrome)

First-in-Human Study of EOS100850 (Inupadenant) in Patients with Cancer

Prostate Imaging Using MRI +/- Contrast Enhancement

A Study of CC-95251, a Monoclonal Antibody Directed Against SIRPα, in Participants With Advanced Solid and Hematologic Cancers

Target Controlled Infusion Using Propofol and Remifentanil for Moderate Sedation in Dentistry