Clinical Trials in Maryland

Showing 17201-17220 of 23,284 trials

COMPLETEDPhase 113 miles

Safety and Immunogenicity Study of a Dengue Virus DNA Vaccine

NCT00290147

The purpose of this study is to exame the safety of a DNA vaccine against dengue-1.

Dengue

U.S. Army Medical Research and Development Command22 participantsStarted Jan 2006

Silver Spring, Maryland, United States

COMPLETEDPhase 2/314 miles

Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients

NCT01061736

Primary Objectives: Part A (dose ranging study): To demonstrate that sarilumab (SAR153191/REGN88) on top of MTX was effective on reduction of signs and symptoms of rheumatoid arthritis at 12 weeks. Part B (pivotal study): To demonstrate that sarilumab added to MTX was effective in: * reduction of signs and symptoms of rheumatoid arthritis at 24 weeks * inhibition of progression of structural damage at 52 weeks * improvement in physical function at 16 weeks Secondary Objectives: Part B: To demonstrate that sarilumab added to MTX was effective in induction of a major clinical response at 52 weeks To assess the safety of sarilumab added to MTX To document the pharmacokinetic profile of sarilumab added to MTX in participants with active rheumatoid arthritis who were inadequate responders to MTX therapy.

Rheumatoid Arthritis

Sanofi1,675 participantsStarted Mar 2010

Anniston, Alabama, United States • Birmingham, Alabama, United States • Gilbert, Arizona, United States +259 more locations

Safety and Immunogenicity Study of a Dengue Virus DNA Vaccine

Evaluation of Sarilumab (SAR153191/REGN88) on Top of Methotrexate in Rheumatoid Arthritis Patients

Find Trials by Condition in Maryland

To Evaluate The Safety of SAR153191 (REGN88) and Tocilizumab Added to Other RA Drugs in Patients With RA Who Are Not Responding to or Intolerant of Anti-TNF Therapy (SARIL-RA-ASCERTAIN)

Cetuximab + / - Carboplatin for Estrogen Receptor-Negative, Progesterone Receptor-Negative Metastatic Breast Cancer

Safety Study of the Ventricular Partitioning Device (VPD) Implant System in Heart Failure Patients

S0800, Nab-Paclitaxel, Doxorubicin, Cyclophosphamide, and Pegfilgrastim With or Without Bevacizumab in Treating Women With Inflammatory or Locally Advanced Breast Cancer

Study of Tissue Samples From Patients With Non-Small Cell Lung Cancer

Collection of Patient-Reported Symptoms and Performance Status Via the Internet

Platinum-based Chemoradiotherapy and Rigosertib in Head and Neck Cancer

Comparison Of Molecular Targets In Mild To Severe Asthmatics And Healthy Subjects

A Study of MM-111 and Paclitaxel With Trastuzumab in Patients HER2 Positive Carcinomas of the Distal Esophagus, Gastroesophageal (GE) Junction and Stomach

Evaluation of Immediate Versus Delayed Loading of Dental Implants With a Modified Surface

BioFiber Scaffold Post-Market Observational Study

A First Time in Human Study to Assess GSK2336805 in Healthy Volunteers and Single Doses in Chronically Infected Hepatitis C Patients.

Efficacy and Safety of Oral Rigosertib in Transfusion-dependent, Low or Int-1 or Trisomy 8 Int-2 Myelodysplastic Syndrome

Safety and Pharmacokinetic Study of Oral ON 01910.Na in Patients With Myelodysplastic Syndrome

A Study of TRU-016 in Combination With Rituximab and Bendamustine in Subjects With Relapsed Indolent Lymphoma

Study of Voreloxin (Vosaroxin) in Older Patients With Untreated Acute Myeloid Leukemia

Evaluating Processes of Care & the Outcomes of Children in Hospital (EPOCH)

Impact of SBI, a Medical Food, on Nutritional Status in Patients With HIV-associated Enteropathy