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Discover 23,284 clinical trials near Maryland. Find research studies in your area.
Showing 16661-16680 of 23,284 trials
NCT00316485
Under this study, patients who require removal of their third molars (wisdom teeth) will be diagnosed, evaluated and treated. In addition, tooth, bone and gum tissue samples will be collected for use in bone, wound healing, microbiology and genetic research. Patients 16-50 years of age who require wisdom tooth removal may be eligible for this study. Participants may have one or all of their wisdom teeth removed at one time. The surgery is done under local anesthetic. In addition, conscious sedation may be administered, if the patient wishes. Besides wisdom tooth removal, patients are asked to donate a small sample of jaw bone (from the lining of the inner wall of the tooth socket) and gum tissue (from the area of the surgical site). The samples are collected at the same time as the tooth extraction. The bone sample is about the size of a pencil point (1.5 millimeters wide and 3 millimeters long) and the gum tissue sample is 1 millimeter. Removal of these samples should not cause any additional discomfort or increase the time required for the surgery or for healing.
NCT01020318
Background: * Traumatic brain injury (TBI) is a significant injury in the Armed Forces, but it is also common in the general population. This condition poses significant challenges for both diagnosis and therapy. However, the biological and neurological reasons for TBI remain poorly understood and are in need of more in-depth study. * The National Institutes of Health is collaborating with several military medical centers and research units in a multi-year study of TBI in civilian and military patients. In anticipation of these research projects, the Clinical Center s Rehabilitation Medicine Department needs to become familiar with the instruments they will likely need to evaluate this group of subjects. Objectives: * To evaluate potential test instruments in patients with TBI. * To evaluate patient tolerance of an extensive battery of assessments and the time required to complete the assessments. * To improve staff competencies on new or novel assessments of the TBI patient population Eligibility: * Individuals 18 years of age and older who have been diagnosed with a traumatic brain injury in the past 5 years. * Healthy volunteers 18 years of age and older who have had no instances of significant head trauma. Design: * This study requires approximately 3 days of outpatient or inpatient evaluation. * Subjects will undergo cognitive and neuropsychological tests, physical assessments, speech and language evaluation, and balance testing. Tests will be given orally, in writing, and on computers. The testing will be done in blocks of 2 to 3 hours, with rest periods as needed. * Subjects may undergo any or all of the following assessments and screening tools, as determined by the researchers: * Cognitive, quality of life, and functional assessments * Speech, language, and swallowing assessments * Physical functional performance and environment assessments (including balance testing) * Subjects will remain under the care of their own health care providers while participating in this study.