Clinical Trials in Maryland

Showing 12541-12560 of 19,983 trials

Immune-Modulated Study of Selected Small Molecules (Gefitinib, AZD9291, or Selumetinib + Docetaxel) or a 1st Immune-Mediated Therapy (IMT; Tremelimumab) With a Sequential Switch to a 2nd IMT (MEDI4736) in Patients With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer

NCT02179671

Primary objective: To assess the efficacy of various sequences of either a small molecule or an IMT (IMT-A) followed by a IMT-B (MEDI4736) .

Locally Advanced or Metastatic Non-Small-Cell Lung Cancer (Stage IIIB-IV)

AstraZeneca32 participantsStarted Jul 2014

Goodyear, Arizona, United States • Washington D.C., District of Columbia, United States • Augusta, Georgia, United States +7 more locations

COMPLETEDPhase 317 miles

A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]

NCT02302807

This is a Phase III, global, multicenter, open-label, two-arm, randomized, controlled study designed to evaluate the efficacy and safety of atezolizumab compared with chemotherapy in participants with locally advanced or metastatic urothelial bladder cancer (UBC) who have progressed during or following a platinum-containing regimen. The anticipated time on study treatment is based on continued clinical benefit, i.e., until disease progression or unacceptable toxicity. The target sample size is 931 participants.

Bladder Cancer

Hoffmann-La Roche931 participantsStarted Jan 2015

Washington D.C., District of Columbia, United States • Atlanta, Georgia, United States • Las Vegas, Nevada, United States +214 more locations

Immune-Modulated Study of Selected Small Molecules (Gefitinib, AZD9291, or Selumetinib + Docetaxel) or a 1st Immune-Mediated Therapy (IMT; Tremelimumab) With a Sequential Switch to a 2nd IMT (MEDI4736) in Patients With Locally Advanced or Metastatic Non-Small-Cell Lung Cancer

A Study of Atezolizumab Compared With Chemotherapy in Participants With Locally Advanced or Metastatic Urothelial Bladder Cancer [IMvigor211]

Find Trials by Condition in Maryland

Safety and Immunogenicity of the Na-APR-1 Hookworm Vaccine in Healthy Adults

Down Syndrome Metabolic Health Study

Mechanisms of Sleep Disruption Hyperalgesia

Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 Diabetes

A Blinded Study to Evaluate Effect on Atrial Fibrillation Burden in Patients With Paroxysmal Atrial Fibrillation

Early Treatment of Amyotrophic Lateral Sclerosis (ALS) With Nutrition and Non-Invasive Positive Pressure Ventilation

Study Evaluating Chemotherapy in Combination With Inotuzumab Ozogamicin In Subjects With Non-Hodgkin's Lymphoma

Phase 2 Study to Evaluate the Microbiology and Safety of C16G2 Administered to Adult and Adolescent Dental Subjects

Study of MLN8237 in Combination With Irinotecan and Temozolomide

A Study to Evaluate BMS-986036 in Obese Adults With Type-2 Diabetes

Evaluation of Capsule Endoscopy With PillCam® COLON 2 in Visualization of the Colon

Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) Preparation and Procedure

Multiple Ascending Dose of BMS-911543

Evaluation of the PillCam™ Colon Capsule Endoscopy (PCCE) in the Visualization of the Colon

Prevention of S. Aureus Pneumonia Study in Mechanically Ventilated Subjects Who Are Heavily Colonized With S. Aureus.

STREAM-Strategic Reperfusion (With Tenecteplase and Antithrombotic Treatment) Early After Myocardial Infarction

Different Therapies in Treating Infants With Newly Diagnosed Acute Leukemia

An Open-Label Extension Study Assessing the Long-Term Efficacy and Safety of ALX-0061 in Subjects With Rheumatoid Arthritis