Clinical Trials in Maryland

Showing 2241-2260 of 11,119 trials

Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy

NCT05374447

The investigators will compare endobronchial ultrasound transbronchial needle aspiration (EBUS-TBNA) with intranodal forceps biopsy (EBUS-IFB) as it relates to the rate of diagnosis of suspected sarcoidosis.

Mediastinal LymphadenopathySarcoidosis, PulmonaryMediastinal Diseases

George Washington University55 participantsStarted Jun 2022

Washington D.C., District of Columbia, United States

TERMINATEDPhase 317 miles

Efficacy and Safety of Tolebrutinib (SAR442168) Tablets in Adult Participants With Generalized Myasthenia Gravis

NCT05132569

This was a multicenter, randomized, double-blind, placebo-controlled, Phase 3 study to evaluate the efficacy and safety of tolebrutinib compared with placebo in adult participants aged 18 to 85 years old with moderate-to-severe generalized myasthenia gravis (gMG), who received Standard of Care (SoC). The double-blind (DB) treatment period of 26 weeks comprised of 7 site visits followed by a 2-year open label extension (OLE) period with quarterly visits. The efficacy of tolebrutinib versus placebo during the DB period was assessed by clinical evaluations, including scales based on physician examination or direct participant feedback i.e., patient reported outcomes (PROs). These evaluations continued during the OLE to measure long term efficacy and safety.

Myasthenia Gravis

Sanofi6 participantsStarted Dec 2021

Washington D.C., District of Columbia, United States • Boca Raton, Florida, United States • Tampa, Florida, United States +19 more locations

Diagnostic Yield of Intranodal Forceps Biopsies in Mediastinal Adenopathy

Efficacy and Safety of Tolebrutinib (SAR442168) Tablets in Adult Participants With Generalized Myasthenia Gravis

Find Trials by Condition in Maryland

A Study of mRNA-1010 Compared With a Licensed Influenza Vaccine in Adults ≥50 Years of Age

Trial of Anti-Tim-3 in Combination With Anti-PD-1 and SRS in Recurrent GBM

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Prospective Registry for Long-term Outcomes Following FETO in Severe Left and Right CDH

A Prospective, US-based Study Assessing Mogamulizumab-associated Rash in Patients Diagnosed With Mycosis Fungoides or Sezary Syndrome and Treated With Standard of Care Mogamulizumab

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

A Study of LM-24C5 For Advanced Solid Tumors

First-in-Human Study of OKI-219 in Advanced Solid Tumors and Advanced Breast Cancer

ACHIEVE Hearing Intervention Follow-Up Study

Examining Distinct Immunophenotypes to Validate and Enhance Rational Treatment in Systemic Lupus

Study to Evaluate the Efficacy & Safety of the INTERCEPT Blood System for RBCs in Complex Cardiac Surgery Patients

A Trial of Centanafadine Efficacy, Safety, and Tolerability in Adult Subjects With Binge Eating Disorder

Retrospective Study of Suture Tape for Soft Tissue Reconstruction in Patients Suffering From Lateral Ankle Instability

OCS DCD Heart + CAP Continued Follow-Up

A Study Comparing Venetoclax and Azacitidine Plus Cusatuzumab to Venetoclax and Azacitidine in Newly Diagnosed AML Ineligible for Intensive Therapy

A Phase 2 Study of YA-101 in Patients With Multiple System Atrophy

Safety of Simultaneous mRNA COVID-19 Vaccine With Other Childhood Vaccines in Young Children

A Study of Belrestotug Plus Dostarlimab Compared With Placebo Plus Pembrolizumab in Previously Untreated Participants With Programmed Death Ligand 1 (PD-L1) High Non-small-cell Lung Cancer (NSCLC)