Clinical Trials in Los Angeles

Showing 16181-16200 of 16,901 trials

Brain Mechanisms and Targeting Insomnia in Major Depression

NCT00628914

Preliminary studies suggest that the response to antidepressant medication can be accelerated by targeting insomnia with adjunctive use of eszopiclone. It is not yet known what mechanism(s) support this acceleration in response, though preliminary findings support the hypothesis that early restoration of sleep may facilitate BDNF-based effects of antidepressant medications. The optimal duration of co-treatment is also unknown. This study will test specific hypotheses about brain mechanisms and evaluate the effects of continued eszopiclone beyond the time window when response acceleration should be observed.

Major Depressive DisorderInsomnia

University of California, Los Angeles60 participantsStarted May 2008

Los Angeles, California, United States

COMPLETEDPhase 2< 1 mile

Neuropathic Pain in Patients With Cancer

NCT00474916

The purpose of this study is to collect beginning information on whether intravenous (IV) administration of KRN5500 is safe and effective for treatment of neuropathic pain in patients with cancer.

Neuropathic Pain

DARA Therapeutics19 participantsStarted Jun 2006

Los Angeles, California, United States • Los Angeles, California, United States • Orange, California, United States +9 more locations

Brain Mechanisms and Targeting Insomnia in Major Depression

Neuropathic Pain in Patients With Cancer

Find Trials by Condition in Los Angeles

Building Better Caregivers Online: An Online Workshop for Caregivers of Those With Traumatic Brain Injury, Post Traumatic Stress Disorder, or Alzheimer's or Other Dementia

Dasatinib (BMS-354835) Versus Imatinib Mesylate in Subjects With Chronic Myeloid Leukemia

Liver Spare the Nephron (STN) Study - A Study of CellCept (Mycophenolate Mofetil) and Sirolimus in Recipients of a Liver Transplant

Prevention of Atrial Arrhythmia in Patients Without Atrioventricular (AV) Conduction Disease

Open-Label Safety Study to Evaluate Imiquimod Cream, 5% for Large Areas of Actinic Keratosis

A/H5N1 Vaccine in Healthy Children Aged 2-9 Years

Comparative Trial of Entecavir Versus Adefovir in the Treatment of Chronic Hepatitis B Infection

Ribavirin to Prevent RSV Pneumonia in Bone Marrow Transplant Patients

Biological Therapy After Chemotherapy in Treating Patients With Relapsed or Refractory Non-Hodgkin's Lymphoma

Effects of Metformin Hydrochloride (HCl) in Combination With Colesevelam HCl, Compared to Metformin HCl Alone, in Patients With Type 2 Diabetes Mellitus and the Effects of Colesevelam HCl on Lipids and Glucose on Pre-diabetic Patients.

Effect of Bazedoxifene, Raloxifene, and Placebo on Breast Density

Dose-Finding Study of REN-1654 in Patients With Post-Herpetic Neuralgia

Study of AT-101 in Combination With Topotecan in Relapsed/Refractory Small Cell Lung Cancer

Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stent in the Treatment of In-Stent Restenosis

Randomized Trial Evaluating Slow-Release Formulation TAXUS Paclitaxel-Eluting Coronary Stents to Treat De Novo Coronary Lesions

RexMedical- Option* Vena Cava Filter IDE Study

Safety and Immune Response to a Multi-component Immune Based Therapy (MKC1106-PP) for Patients With Advanced Cancer.

Vapreotide in Treating Patients Undergoing Elective Pancreatic Resection