Clinical Trials in Los Angeles

Showing 1461-1480 of 16,901 trials

A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

NCT07207707

The goal of this trial is to learn if KQB548 works to treat patients with advanced solid malignancies with a KRAS G12D mutation. It will also learn about the safety of KQB548. The main questions it aims to answer are: * What is the safe dose of KQB548? * Does KQB548 decrease the size of the tumor? * What happens to KQB548 in the body?

Solid Tumor Malignancies

Kumquat Biosciences Inc.78 participantsStarted Sep 2025

La Jolla, California, United States • Los Angeles, California, United States • Denver, Colorado, United States +9 more locations

TERMINATEDPhase 1< 1 mile

Allopregnanolone Regenerative Therapeutic for Early Alzheimer's Disease: Intramuscular Study

NCT03748303

The purpose of this study is to identifying the intramuscular dose equivalent to the 4mg intravenous dose and assess its safety and tolerability as a weekly injection.

Alzheimer Dementia

University of Arizona6 participantsStarted Oct 2019

Los Angeles, California, United States

Active Not RecruitingPhase 3< 1 mile

A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

NCT04901195

The purpose of the study is to evaluate the safety of long-term therapy of bimekizumab in study participants with moderate to severe hidradenitis suppurativa (HS)

Hidradenitis Suppurativa

UCB Biopharma SRL658 participantsStarted May 2021

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Fountain Valley, California, United States +142 more locations

A Study to Investigate the Safety and Efficacy of KQB548 in Participants With Advanced Solid Malignancies

Allopregnanolone Regenerative Therapeutic for Early Alzheimer's Disease: Intramuscular Study

A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa

Find Trials by Condition in Los Angeles

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]

A Study of Amivantamab Subcutaneous (SC) Administration for the Treatment of Advanced Solid Malignancies

Inclisiran Versus Placebo for the Prevention of Major Adverse Cardiovascular and Limb Events in Patients Undergoing Percutaneous Coronary Intervention or Peripheral Endovascular Intervention

Liquid Biopsy Using Exosomal miRNA Enables Risk Stratification of Potential Metastasis in Patients With Intrahepatic Cholangiocarcinoma.

Nemtabrutinib With Rituximab for the Treatment of Patients With Mantle Cell Lymphoma

A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer

Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease

A Study of Adagrasib Plus Pembrolizumab Plus Chemotherapy vs. Placebo Plus Pembrolizumab Plus Chemotherapy in Participants With Previously Untreated Non-squamous Non-small Cell Lung Cancer With KRAS G12C Mutation (KRYSTAL-4)

Optimizing Reperfusion to Improve Outcomes and Neurologic Function

Long-term Efficacy and Safety of Tozorakimab in Participants With Chronic Obstructive Pulmonary Disease With a History of Exacerbations (PROSPERO).

A Study to Assess the Efficacy and Safety of Empasiprubart Versus IVIg in Adults With Multifocal Motor Neuropathy

Ethnic Influences on Stress, Energy Balance and Obesity in Adolescents

A Study of Patients With Lower Extremity Acute Limb Ischemia to Remove Thrombus With the Indigo™ Aspiration System (STRIDE II)