Clinical Trials in Los Angeles

Showing 9781-9800 of 14,465 trials

Sevelamer for Reducing Endotoxemia and Immune Activation

NCT01543958

HIV-infected people can have an increase in inflammation in their body organs, even after taking anti-HIV medicines. Sevelamer carbonate is used to bind phosphate in dialysis patients. It can also bind endotoxin in the gut and lowers endotoxin levels in the blood of dialysis patients. Sevelamer carbonate decreases the inflammation endotoxin causes in dialysis patients. A5296 is a phase II, single-arm study to evaluate the effect of 8 weeks of sevelamer carbonate administration on markers of microbial translocation and T-cell activation in the blood in chronically HIV-infected subjects not receiving ART.

HIV-1 Infection

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections40 participantsStarted Nov 2011

Birmingham, Alabama, United States • Los Angeles, California, United States • San Francisco, California, United States +12 more locations

COMPLETEDPhase 4< 1 mile

Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings

NCT00084136

This study compared 3 different three-drug combinations in HIV infected individuals starting their first HIV treatment regimens. Participants were recruited from resource-limited areas in Africa, Asia, South America, Haiti, and also from the United States. The study hypothesis was each of the once daily combinations (PI based, or NNRTI based) would not have inferior efficacy compared to the twice daily NNRTI based combination.

HIV Infections

Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections1,571 participantsStarted May 2005

Los Angeles, California, United States • Los Angeles, California, United States • Torrance, California, United States +39 more locations

Sevelamer for Reducing Endotoxemia and Immune Activation

Prospective Evaluation of Anti-retroviral Combinations for Treatment Naive, HIV Infected Persons in Resource-limited Settings

Find Trials by Condition in Los Angeles

Substance Abuse Treatment to HIV Care (SAT2HIV): The Implementation & Sustainment Facilitation Experiment

Perceptions of Side Effects of Cancer Chemoradiotherapy

Study of Epratuzumab Versus Placebo in Subjects With Moderate to Severe General Systemic Lupus Erythematosus

A Study of LY3079514 in Healthy Participants

A Study of LY2484595 in Healthy Subjects

Post-Market Study of the Modular Revision Hip System

A Study Comparing the Efficacy, Safety and Tolerability of Fixed Dose Combination (FDC) of FF/UMEC/VI With the FDC of FF/VI and UMEC/VI; Administered Once-daily Via a Dry Powder Inhaler (DPI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye Disease

A Safety and Efficacy Study of Dapsone Gel in Patients With Acne Vulgaris

Safety and Immunogenicity of 2 or 3 Doses of MenACWY Conjugate Vaccine in Healthy Infants and the Effects of a Booster Dose of MenACWY Administered in the Second Year of Life

PERSEUS: Preliminary Efficacy and Safety of Cenicriviroc in Adult Participants With Primary Sclerosing Cholangitis

Assessing Fitting Guides in Alcon Multifocal Contact Lenses

A Study of the Blood Pressure Lowering Ability and Safety of Olmesartan Medoxomil in Stage I and Stage II Hypertension

A Dose-ranging Study With Brivaracetam in Patients From 16 to 65 Years With Refractory Partial Onset Seizures.

Multicenter Continuous Peripheral Nerve Block Surveillance Study

A Study of Axitinib in Advanced Carcinoid Tumors

A Pilot Study to Evaluate the Use of Smart Adherence Technology to Measure Lumacaftor/Ivacaftor Adherence in CF Subjects Homozygous for the F508del CFTR Mutation

Safety, Efficacy, Dose-finding Study of a Monoclonal Antibody in Patients With Multiple Myeloma