Clinical Trials in Los Angeles

Showing 8921-8940 of 16,901 trials

Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies

NCT02985021

In this study, patients who have metastatic prostate cancer that does not respond to hormone treatment and who have mutations in certain cancer-related genes will be treated with docetaxel and carboplatin chemotherapy.

Hormone-Resistant Prostate CancerMetastatic Prostate CarcinomaRecurrent Prostate Carcinoma+1 more

Seattle Institute for Biomedical and Clinical Research2 participantsStarted Nov 2016

Los Angeles, California, United States • Ann Arbor, Michigan, United States • Seattle, Washington, United States

COMPLETEDNA< 1 mile

Development and Validation of a Digital Pain-Reduction Kit for Musculoskeletal Injuries

NCT03187132

This study will test the effectiveness of an evidence-based, multi-modal, "digital pain-reduction kit" as a non-pharmacological supplement to managing patients with pain due to musculoskeletal injuries. Outpatients will be randomized to receive either the pain reduction kit or active control. The kit will contain a virtual reality (VR) headset, therapeutic VR visualization software, and a low-cost wearable transcutaneous electrical nerve stimulation (TENS) unit. Clinical staff will monitor progress and provide scheduled coaching and outreach to patients in the intervention group. The control group will receive the low-cost wearable transcutaneous electrical nerve stimulation (TENS) unit alone; they will not receive VR or remote coaching. Study devices will be delivered to the patient's home with instructions for use; patients will receive remote clinical and technical support. Patients will be followed for 60 days and monitored for functional status, pain levels, use of pain medications (including opioids), satisfaction with care, and time to returning to work.

Pain, AcutePain, Chronic

Cedars-Sinai Medical Center245 participantsStarted Apr 2018

Los Angeles, California, United States

Docetaxel and Carboplatin for Patients With mCRPC and DNA-Repair Deficiencies

Development and Validation of a Digital Pain-Reduction Kit for Musculoskeletal Injuries

Find Trials by Condition in Los Angeles

Brain and Behavior Correlates of Arm Rehabilitation

Maraviroc to Augment Rehabilitation Outcomes After Stroke

A Study To Investigate Tanezumab In Patients With Interstitial Cystitis/ Painful Bladder Syndrome

IMPAACT P1080: Psychiatric and Antiretroviral Medication Concentrations in HIV-infected and Uninfected Children and Adolescents

Study to Test the Safety, Tolerability and Efficacy of UCB7665 in Subjects With Moderate to Severe Myasthenia Gravis

Telmisartan to Reduce AIDS-Related Fibrotic and Inflammatory Contributors (TRAFIC Study)

Evaluating the Safety and Tolerability of the Poly-ADP Ribose (PARP) Inhibitor With FOLFIRI in Subjects With Solid Tumor

Single Versus Combination Medication Treatment for Children With Attention Deficit Hyperactivity Disorder

Open Label, Phase III Study of NABI-IGIV 10% [Immune Globulin Intravenous(Human), 10%] In Subjects With Primary Immune Deficiency Disorders (PIDD)

Registry of Subject Treated With ClariFix

Tesetaxel Plus Reduced Dose of Capecitabine in Patients With HER2 Negative, HR Positive, LA/MBC

A Study of CNP520 Versus Placebo in Participants at Risk for the Onset of Clinical Symptoms of Alzheimer's Disease

Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair

A Study To Compare Pregabalin/PF-00489791 Combination Versus Pregabalin Alone In Post-Herpetic Neuralgia

Natural History of Rett Syndrome & Related Disorders

Biobanking of Rett Syndrome and Related Disorders

Acthar for Treatment-Resistant or Treatment-Intolerant Proteinuria

Safety and Efficacy of Sirolimus for HIV Reservoir Reduction in Individuals on Suppressive Antiretroviral Therapy (ART)