Clinical Trials in Los Angeles

Showing 421-440 of 12,794 trials

An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

NCT06447025

An open label study designed to evaluate the safety, PK, PD, and clinical effects of long-term daily administration of CTI-1601 enrolling patients with FRDA who have participated in a prior clinical study of CTI-1601 as well as adolescents and adults with FRDA who have not participated in a prior clinical study of CTI-1601.

Friedreich Ataxia

Larimar Therapeutics, Inc.85 participantsStarted Jan 2024

Los Angeles, California, United States • Gainesville, Florida, United States • Tampa, Florida, United States +5 more locations

RECRUITING< 1 mile

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

NCT06465810

The MaesTTRo study aims to enroll a global cohort of patients with transthyretin (ATTR) amyloidosis to longitudinally observe the natural course of the disease and describe real-world treatment patterns and outcomes. In addition, information on the effectiveness of ATTR amyloidosis treatments, including eplontersen, which is a ligand-conjugated antisense oligonucleotide gene silencing treatment targeting activity against both the mutant and wild-type TTR protein, will be collected.

Transthyretin AmyloidosisATTR-CMATTRv-PN+3 more

AstraZeneca1,850 participantsStarted Jun 2024

La Jolla, California, United States • Los Angeles, California, United States • San Francisco, California, United States +50 more locations

An Open-Label Study of CTI-1601 in Subjects With Friedreich's Ataxia

Non-interventional Study of Patients With Transthyretin (ATTR) Amyloidosis

Find Trials by Condition in Los Angeles

A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis

fNIRS for Disorders of Consciousness

A Study to Evaluate Pharmacokinetics of LY3209590 in Pediatric Participants With Type 2 Diabetes Mellitus

Neuroblastoma Biology Study

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

An Assessment of Efficacy, Safety, and Pharmacokinetics of NBI-1117568 in Adults With Bipolar I Disorder With Current Mania

A Study of Enfortumab Vedotin Alone or With Other Therapies for Treatment of Urothelial Cancer

Efficacy and Safety of Zanidatamab With Standard-of-care Therapy Against Standard-of-care Therapy for Advanced HER2-positive Biliary Tract Cancer

A Phase I/II Study on Safety AND Immunogenicity of AZD4117 and AZD5315 Vaccines (PANDA)

Low PSMA SUV Boost (LPS-Boost): Intensified 177Lu-PSMA-617 Treatment for Patients With Metastatic Castrate-Resistant Prostate Cancer With Low PSMA Expressing Disease

Double-blind, Placebo-controlled Study in Adults With Major Depressive Disorder

Exercise in Child Health

Early Parkinson's Disease Monotherapy With CVN424

QUELIMMUNE (SCD-PED) PediAtric SurVeillance REgistry

An Efficacy and Safety Study of Cofetuzumab Pelidotin in Participants With PTK7-Expressing, Recurrent Non-Small Cell Lung Cancer

Ruxolitinib in Combination With Venetoclax With and Without Azacitidine in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study