Clinical Trials in Los Angeles

Showing 3681-3700 of 16,901 trials

Intermittent Theta Burst Stimulation for MDD

NCT02506127

This study will evaluate the effectiveness of intermittent Theta Burst Stimulation for patients with Major Depressive Disorder.

Major Depressive Disorder

University of California, Los Angeles30 participantsStarted Dec 2017

Los Angeles, California, United States

COMPLETEDPhase 3< 1 mile

Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

NCT00371033

The purpose of this study is to determine whether pregabalin is an effective treatment for Chronic Prostatitis/Chronic Pelvic Pain Syndrome.

Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)324 participantsStarted Mar 2006

Los Angeles, California, United States • Los Angeles, California, United States • Stanford, California, United States +8 more locations

RECRUITINGNA< 1 mile

Model-based Electrical Brain Stimulation

NCT05327387

Neuropsychiatric disorders are a leading cause of disability worldwide with depressive disorders being one of the most disabling among them. Also, millions of patients do not respond to current medications or psychotherapy, which makes it critical to find an alternative therapy. Applying electrical stimulation at various brain targets has shown promise but there is a critical need to improve efficacy. Given inter- and intra-subject variabilities in neuropsychiatric disorders, this study aims to enable personalizing the stimulation therapy via i) tracking a patient's own symptoms based on their neural activity, and ii) a model of how their neural activity responds to stimulation therapy. The study will develop the modeling elements needed to realize a model-based personalized system for electrical brain stimulation to achieve this aim. The study will provide proof-of-concept demonstration in epilepsy patients who already have intracranial electroencephalography (iEEG) electrodes implanted for their standard clinical monitoring unrelated to this study, and who consent to being part of the study.

Medication Refractory Epilepsy Patients With Electrodes Already Implanted Based on Clinical Criteria for Standard Monitoring

University of Southern California25 participantsStarted Feb 2022

Los Angeles, California, United States • San Francisco, California, United States

Intermittent Theta Burst Stimulation for MDD

Efficacy & Safety Study of Pregabalin to Treat Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS)

Model-based Electrical Brain Stimulation

Find Trials by Condition in Los Angeles

A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin

A Study to Evaluate the Efficacy and Safety of Erenumab in Adults With Medication Overuse Headache

A Phase I Study of IAG933 in Patients With Advanced Mesothelioma and Other Solid Tumors

Dexmedetomidine in the Treatment of Agitation Associated With Schizophrenia and Bipolar Disorder (SERENITY III)

Study of Recombinant Protein Vaccines With Adjuvant as a Primary Series and as a Booster Dose Against COVID-19 in Adults 18 Years of Age and Older

A Study to Evaluate Mavacamten Impact on Myocardial Structure in Participants With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Study to Explore the Therapeutic Effect of Eluxadoline in Treating Irritable Bowel Syndrome With Diarrhea in Children

Long COVID-19 Rehabilitation & Recovery Research Program

External Beam Radiation Therapy in Combination With Talquetamab for the Treatment of Multiple Myeloma Patients With Extramedullary Disease

AOH1996 for the Treatment of Refractory Solid Tumors

Cobimetinib in Refractory Langerhans Cell Histiocytosis (LCH), and Other Histiocytic Disorders

Evaluation of Fluoxetine and Cytotoxic Lysosomal Stress in Glioma (FLIRT)

Long-term Safety and Efficacy Evaluation of Subcutaneous Amlitelimab in Adult Participants With Moderate-to-severe Asthma Who Completed Treatment Period of Previous Amlitelimab Asthma Clinical Study

Clinical Effectiveness Assessment of VeriStrat® Testing and Validation of Immunotherapy Tests in NSCLC Subjects

4D-150 in Patients With Diabetic Macular Edema

Nodify XL2 Classifier Clinical Utility Study in Low to Moderate Risk Lung Nodules

Short-course Regimens for the Treatment of Pulmonary Tuberculosis