Clinical Trials in Illinois

Showing 1881-1900 of 19,692 trials

Expanded Access to Bezuclastinib for Patients With NonAdvanced Systemic Mastocytosis or Advanced Systemic Mastocytosis

NCT06915766

The purpose of this expanded access program (EAP) protocol is to provide investigational bezuclastinib to patients with a diagnosis of nonadvanced systemic mastocytosis (NonAdvSM) or advanced systemic mastocytosis (AdvSM) who have received and failed or been intolerant to at least one standard approved therapy and/or have no comparable or satisfactory alternative therapy options.

Systemic Mastocytoses, IndolentSystemic Mastocytoses, Aggressive

Cogent Biosciences, Inc.

La Jolla, California, United States • La Jolla, California, United States • Los Angeles, California, United States +15 more locations

RECRUITING40 miles

SuperSaturated Oxygen Comprehensive Observational Registry

NCT06438315

The SuperSaturated Oxygen Comprehensive Observational Registry (SSCORE) registry, a prospectively designed observational study, aims to evaluate the clinical utility and effectiveness of SuperSaturated Oxygen (SSO2) Therapy versus percutaneous coronary intervention (PCI) alone among patients with anterior acute myocardial infarction (AMI) in routine clinical practice. The goal is to collect real-world data from patients treated with SSO2 Therapy to determine its impact on the overall heart failure (HF) burden on patients and healthcare systems compared with usual care for treatment of patients with AMI. The SSCORE Registry will generate effectiveness and healthcare resource utilization data that will be used in cost-effectiveness analysis modeling.

STEMI - ST Elevation Myocardial InfarctionAMI

TherOx1,000 participantsStarted Aug 2024

Fountain Valley, California, United States • La Jolla, California, United States • Laguna Hills, California, United States +20 more locations

Expanded Access to Bezuclastinib for Patients With NonAdvanced Systemic Mastocytosis or Advanced Systemic Mastocytosis

SuperSaturated Oxygen Comprehensive Observational Registry

Find Trials by Condition in Illinois

Clinical Trial of Lurbinectedin as Single-agent or in Combination With Irinotecan Versus Topotecan or Irinotecan in Patients With Relapsed Small-cell Lung Cancer (LAGOON)

Study of V117957 in Interstitial Cystitis/Bladder Pain Syndrome

A Study of Tagraxofusp in Combination With Venetoclax and Azacitidine in Adults With Untreated CD123+ Acute Myeloid Leukemia Who Cannot Undergo Intensive Chemotherapy

A Trial of Eptinezumab in Participants With Migraine and Insufficient Response to Anti-CGRP Medications

Study to Evaluate the PK of IV and PO Omadacycline in Children and Adolescents With Suspected or Confirmed Bacterial Infections

ARX788 in HER2-positive, Metastatic Breast Cancer Subjects (ACE-Breast-03)

A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis

AZD0901 Compared With Investigator's Choice of Therapy in Participants With Second- or Later-line Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Expressing Claudin18.2

A Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast Cancer

Direct Access Carotid Artery Stenting Using the Neuroguard IEP System (PERFORMANCE III)

A Study of LY4167586 in Participants With Obesity or Overweight Who Are Otherwise Healthy

A Study of AAVB-039 in Participants With Stargardt Disease (STGD1)

ECD-Score: a Study on Erdheim-Chester Disease

IBI363 vs Docetaxel in Patients With Advanced Squamous Lung Cancer After Standard Treatments Have Failed

A Study to Evaluate the Efficacy and Safety of Intravenous (IV) Prasinezumab in Participants With Early-Stage Parkinson's Disease

Colonoscopy or Fecal Occult Blood Test in Screening Healthy Participants for Colorectal Cancer

REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

A Study in People With Idiopathic Pulmonary Fibrosis to Test Whether Pirfenidone Influences the Amount of BI 1015550 in the Blood