REGN7508 Versus Apixaban and Enoxaparin for Thromboprophylaxis After Total Knee Arthroplasty in Adults

Exclusion Criteria

• •1. Any condition that, as assessed by the investigator, may confound the results of the study or pose an additional risk to the participant by study participation
• •2. History of bleeding in the 6 months prior to randomization requiring hospitalization or transfusion as described in the protocol
• •3. History of thromboembolic disease or thrombophilia
• •4. History of major surgery, including brain, spinal, or ocular, or major trauma within approximately the past 6 months prior to randomization
• •5. Has an estimated Glomerular Filtration Rate (GFR) of \<30 mL/min/1.73 m2 at the screening visit as described in the protocol