Clinical Trials in Illinois

Showing 3961-3980 of 19,692 trials

Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

NCT05918575

Around 20% of the obese patients with higher body mass index (BMI) who are taken off the breathing tube and breathing machine (ventilator) end up needing it back to support breathing. The re-application of breathing tube is associated with poor outcomes, including high risk of pneumonia, longer hospital stays, and death. The purpose of this study is to assess if prophylactic use of noninvasive breathing support after removing the breathing tube lowers the chance of needing the breathing tube again.

Obesity, MorbidExtubation Failure

Rush University Medical Center250 participantsStarted Jul 2023

Chicago, Illinois, United States • Winfield, Illinois, United States • Houston, Texas, United States +2 more locations

RECRUITINGPhase 1125 miles

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

NCT06376162

The primary objective of the study is to determine the recommended phase 2 dose (RP2D) of ziftomenib in combination with chemotherapy (FLA) in children with relapsed or refractory KMT2A-r, NUP98-r, or NPM1-m acute leukemia based on safety and pharmacokinetics (PK).

Relapsed/Refractory KMT2A-r Acute LeukemiaRelapsed/Refractory NUP98-r Acute LeukemiaRelapsed/Refractory NPM1-m Acute Leukemia

PedAL BCU, LLC20 participantsStarted Mar 2025

Los Angeles, California, United States • Aurora, Colorado, United States • Atlanta, Georgia, United States +17 more locations

Postextubation Use of Noninvasive Respiratory Support in Severely Obese Patients

Ziftomenib in Combination With Chemotherapy for Children With Relapsed/Refractory Acute Leukemia

Find Trials by Condition in Illinois

A Study of Zolbetuximab (IMAB362) in Adults With Gastric Cancer

A Clinical Trial in Healthy Volunteers and Volunteers With Recurrent Genital Herpes to Study the Safety, Tolerability, and Immune Responses After Vaccination With an Investigational Vaccine Designed to Prevent Genital Herpes Lesions

Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS)

An Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.

Personalized Therapy Study - HFRS (TriageHF) Post Approval Study

A Study in Patients With Atopic Eczema to Test How Effective BI 655130 is and How Well it is Tolerated

Abbott Ventricular Tachycardia PAS

IN.PACT™ AV Access Post-Approval Study (PAS002)

A Study of Orforglipron (LY3502970) in Participants With Type 2 Diabetes and Inadequate Glycemic Control With Insulin Glargine, With or Without Metformin and/or SGLT-2 Inhibitor

Gilteritinib for the Treatment of ALK NSCLC

BeCoMe-9: A Clinical Study of BE-101 for the Treatment of Adults With Moderately Severe or Severe Hemophilia B

PUSH-IT Continuing Enteral Feeds for Tracheostomy

A Single-ascending Dose (Part A) and Repeat-dose (Part B) Study to Investigate the Safety, Pharmacokinetics and Efficacy (Part B Only) of UCB1381 in Healthy Study Participants (Part A) and in Study Participants With Moderate to Severe Atopic Dermatitis (Part B)

Improving Postamputation Functioning by Decreasing Phantom Pain With Perioperative Continuous Peripheral Nerve Blocks: A Department of Defense Funded Multicenter Study

Staphylococcus Aureus Network Adaptive Platform Trial

Retro Comparison of Subsidence Following Interbody Devices in Lumbar Spine

Prospective Healthcare-Associated Links in Transmission of Nontuberculous Mycobacteria

A Study to Investigate the Antiviral Effect, Safety, Tolerability and Pharmacokinetics of VH3739937 in in Treatment-Naive Adults Living With HIV-1