Clinical Trials in Illinois

Showing 3681-3700 of 19,692 trials

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

NCT05275478

This is a first in human study in patients with advanced or metastatic solid tumors known to have an MTAP deletion. The first part of the study is an open-label, dose escalation and the second part is an open label dose expansion in specific MTAP-deleted tumor types. The study drug, TNG908, is a selective PRMT5 inhibitor administered orally. The study is planned to treat up to 192 participants.

Locally Advanced Solid Tumor

Tango Therapeutics, Inc.192 participantsStarted Mar 2022

Los Angeles, California, United States • San Francisco, California, United States • Denver, Colorado, United States +17 more locations

Active Not RecruitingNA44 miles

M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study

NCT04982835

Prospective, concurrently controlled, multi-center study to evaluate the safety and effectiveness of the Spinal Kinetics M6-C™ artificial cervical disc compared to anterior cervical discectomy and fusion (ACDF) for the treatment of contiguous two-level symptomatic cervical radiculopathy at vertebral levels from C3 to C7 with or without spinal cord compression.

Cervical Disc Degenerative Disorder

Orthofix Inc.156 participantsStarted Jul 2021

Phoenix, Arizona, United States • Beverly Hills, California, United States • Long Beach, California, United States +18 more locations

Safety and Tolerability of TNG908 in Patients With MTAP-deleted Solid Tumors

M6-C Artificial Cervical Disc Two-Level IDE Pivotal Study

Find Trials by Condition in Illinois

STOP Persistent AF PAS

Trametinib in Treating Patients With Recurrent or Progressive Low-Grade Ovarian Cancer or Peritoneal Cavity Cancer

A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa

The PEERLESS Study

A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

Study of LAU-7b for the Treatment of Coronavirus Disease 2019 (COVID-19) Disease in Adults

Study of COPD Subgroups and Biomarkers

Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

A Study Investigating Long-term Treatment With Spesolimab in People With a Skin Disease Called Hidradenitis Suppurativa Who Completed a Previous Clinical Trial

Integrity Implant System Post Market Clinical Follow-Up Study

A Study to Assess the Long-term Efficacy and Safety of AXS-12 (Reboxetine) in Subjects With Narcolepsy (ENCORE)

Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid Cancer

A Trial Evaluating TG4050 in Ovarian Carcinoma.

PROMIS and Mobility Evaluation in Sarcoma Patients

A Study of PF-06873600 in People With Cancer

Safety and Effectiveness of the Sight Sciences VISCO™360 Versus SLT in Primary Open Angle Glaucoma