Efficacy and Safety of Dexlansoprazole MR and Lansoprazole on Healing of Erosive Esophagitis

Exclusion Criteria

• •Subject has a positive Campylobacter-like organisms (CLO) test for Helicobacter (H.) pylori.
• •Use of prescription or non-prescription proton pump inhibitors (PPIs), histamine (H2) receptor antagonists or sucralfate, drugs with significant anticholinergic effects, misoprostol or prokinetics
• •Use of antacids \[except for study supplied Gelusil®\]
• •Need for continuous anticoagulant therapy (Blood Thinners)
• •Endoscopic Barrett's esophagus and/or definite dysplastic changes in the esophagus
• •History of dilatation of esophageal strictures, other than Schatzki's ring (a ring of mucosal tissue near the lower esophageal sphincter)
• •Current or historical evidence of Zollinger-Ellison syndrome or other hypersecretory condition
• •History of gastric, duodenal or esophageal surgery except simple oversew of an ulcer
• •Acute upper gastrointestinal (UGI) hemorrhage within 4 weeks of the Screening endoscopy