Clinical Trials in Houston

Showing 13461-13480 of 15,366 trials

Vorinostat and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors

NCT00243100

This phase I trial is studying the side effects and best dose of vorinostat and gemcitabine in treating patients with metastatic or unresectable solid tumors. Drugs used in chemotherapy, such as vorinostat and gemcitabine, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Vorinostat may also stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor. Giving more than one drug (combination chemotherapy) may kill more tumor cells.

Unspecified Adult Solid Tumor, Protocol Specific

National Cancer Institute (NCI)21 participantsStarted Nov 2005

Houston, Texas, United States

COMPLETEDPhase 3< 1 mile

Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery

NCT00679588

The primary objective is to compare the efficacy and safety of once daily (q.d.) subcutaneous (s.c.) injections of Semuloparin sodium (AVE5026) with q.d. s.c. injections of Enoxaparin for the prevention of Venous Thromboembolic Events (VTE) in patients undergoing major abdominal surgery. The secondary objectives are to evaluate the safety of Semuloparin sodium (AVE5026) and to document Semuloparin sodium (AVE5026) exposure in this population.

Venous Thromboembolism

Sanofi4,413 participantsStarted Apr 2008

Birmingham, Alabama, United States • Birmingham, Alabama, United States • Birmingham, Alabama, United States +267 more locations

Vorinostat and Gemcitabine in Treating Patients With Metastatic or Unresectable Solid Tumors

Evaluation of AVE5026 as Compared to Enoxaparin for the Prevention of Venous Thromboembolism in Patients Undergoing Major Abdominal Surgery

Find Trials by Condition in Houston

The Effect of Weight Loss on Psoriasis Area Severity Index in Adult Psoriasis Patients

Tipifarnib in Treating Patients With Myelodysplastic Syndromes

Interventional Management of Stroke (IMS) III Trial

PROBE Parallel 6-week Treatment Comparing Telmisartan/Hydrochlorothiazide (HCT) (40/12.5 or 80/12.5) With Losartan/HCT (50/12.5) Using Ambulatory Blood Pressure Monitoring (ABPM)

Enteric Coated Myfortic for Liver Transplant Recipients

Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)

Pilot Evaluation of a Walking School Bus Program

Efficacy and Safety Study for the Treatment of Dysfunctional Uterine Bleeding

A Study of Aripiprazole in Patients With Major Depressive Disorder

Assessment of Head Injury in the Emergency Department Using BrainScope® Ahead® Technology

A Study of the Safety, Pharmacokinetics, and Pharmacodynamics of CNTO 3649 in Healthy Adults and Patients With Type 2 Diabetes Mellitus

Effect of QVA149 Versus NVA237 and Tiotropium on Chronic Obstructive Pulmonary Disorder (COPD) Exacerbations

Combination Chemotherapy Plus Filgrastim in Treating Patients With Locally Recurrent or Advanced Urothelium Cancer

Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Single-Dose Subcutaneous Administration of MEDI-528

Combination Chemotherapy Plus Rituximab in Treating Patients With Intermediate-Grade or High-Grade Non-Hodgkin's Lymphoma

A Study Evaluating the Efficacy and Safety of Bevacizumab in Combination With Chemotherapy in Untreated Metastatic Breast Cancer (RIBBON 1)

Study of CS-1008 in Combination With FOLFIRI in Patients Who Have Failed Other Treatments

Combination Chemotherapy in Treating Patients With Prostate Cancer That Has Not Responded to Hormone Therapy