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The purpose of this study is to evaluate the effect that weight loss has on the severity of psoriasis in obese subjects. Fifty obese (BMI equal to or greater than 30) patients with moderate to severe plaque psoriasis will be enrolled in a weight loss intervention program. The severity of their psoriasis will be reevaluated at month 3 and month 6 of the program to determine what effect weight loss has had on their psoriasis. Serum TNF-alpha will be measured at month 0 and month 6. The hypothesis that will be tested is that weight loss will lead to a significant improvement in the severity of psoriasis and a reduction in TNF-alpha levels.
Age
18 - No limit years
Sex
ALL
Healthy Volunteers
No
University of Texas Dermatology Clinical Research
Houston, Texas, United States
Start Date
June 1, 2010
Primary Completion Date
May 1, 2013
Completion Date
May 1, 2013
Last Updated
December 16, 2013
Weight Loss
BEHAVIORAL
Lead Sponsor
The University of Texas Health Science Center, Houston
Collaborators
NCT07472881
NCT01143454
Data Source & Attribution
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