Clinical Trials in Houston

Showing 8521-8540 of 13,620 trials

Dose-finding Study Comparing Efficacy and Safety of a PARP Inhibitor Against Doxil in BRCA+ve Advanced Ovarian Cancer

NCT00628251

The purpose of the study is to compare the efficacy and safety of 2 doses of drug AZD2281 against liposomal doxorubicin to see which is effective and well tolerated in treating patients with measurable BRCA1- or BRCA2-positive advanced ovarian cancer and who have failed previous platinum therapy.

Ovarian Neoplasms

AstraZeneca97 participantsStarted Jul 2008

Los Angeles, California, United States • San Francisco, California, United States • Boca Raton, Florida, United States +21 more locations

COMPLETEDPhase 3< 1 mile

Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy

NCT02065791

The goal of this study is to assess whether canagliflozin has a renal and vascular protective effect in reducing the progression of renal impairment relative to placebo in participants with type 2 diabetes mellitus (T2DM), Stage 2 or 3 chronic kidney disease (CKD) and macroalbuminuria, who are receiving standard of care including a maximum tolerated labeled daily dose of an angiotensin-converting enzyme inhibitor (ACEi) or angiotensin receptor blocker (ARB).

Diabetes Mellitus, Type 2Diabetic Nephropathy

Janssen Research & Development, LLC4,401 participantsStarted Feb 2014

Birmingham, Alabama, United States • Montgomery, Alabama, United States • Tempe, Arizona, United States +572 more locations

Dose-finding Study Comparing Efficacy and Safety of a PARP Inhibitor Against Doxil in BRCA+ve Advanced Ovarian Cancer

Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy

Find Trials by Condition in Houston

Masitinib in Severe Indolent or Smoldering Systemic Mastocytosis

Phase III Trans-Arterial Chemo-Embolization (TACE) Adjuvant HCC

Volixibat (SHP626) in the Treatment of Adults With Nonalcoholic Steatohepatitis (NASH)

Trial of Romidepsin and Bortezomib for Multiple Myeloma

Prevention of Travelers' Diarrhea in Subjects Traveling Outside the U.S.

Study of Dose-dense Adriamycin Plus Cytoxan (AC) Followed by Either ABI-007 (Abraxane) or Taxol With Bevacizumab as Adjuvant Therapy for Patients With Breast Cancer

Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid Arthritis

Mechanisms of Improved Wound Healing and Protein Synthesis of Insulin and Metformin

ImageReady(TM) MR Conditional Pacing System Clinical Study

Phase 4: Investigational Study to Evaluate Metformin XR Monotherapy Versus Metformin IR Monotherapy in Subjects With Type 2 Diabetes

Safety and Efficacy Study of Sebelipase Alfa in Participants With Lysosomal Acid Lipase Deficiency

Post Market Surveillance Study of the Wingspan Stent System

HW006 LATERAL Thoracotomy

Study to Determine the Immunogenicity and Safety of GlaxoSmithKline (GSK) Biologicals; Infanrix Hexa at 2, 4 and 6 Months of Age in Healthy Infants

A Phase 3a, Repeat Dose, Open-label, Long-term Safety Study of Mepolizumab in Asthmatic Subjects

MM-398 (Nanoliposomal Irinotecan, Nal-IRI) to Determine Tumor Drug Levels and to Evaluate the Feasibility of Ferumoxytol Magnetic Resonance Imaging to Measure Tumor Associated Macrophages and to Predict Patient Response to Treatment

PF-06741086 Multiple Dose Study in Severe Hemophilia

A Clinical Trial of IntensiVE Dialysis