Open Label Study of Duloxetine for the Treatment of Phantom Limb Pain

Pilot Study of Use of Duloxetine for the Treatment of Phantom Limb Pain

NCT00425230•Baylor College of Medicine

Summary

This is a study to assess the possible benefit of duloxetine in the treatment of chronic phantom limb pain.

Eligibility

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

Yes

•1. Chronic PLP \> 6 months
•2. Short-Form McGill Pain Questionnaire Sensory Pain Rating Index raw score ≥ 16
•3. Age ≥ 18 years old
•4. Inpatient or Outpatient
•5. Able to come to all appointments, in the opinion of the investigator
•6. Able to give informed consent, in opinion of investigator

•1. Current Major Depressive disorder, Anxiety Disorder, or Psychotic disorder assessed by the Mini International Neuropsychiatric Interview (MINI)
•2. Substance abuse or dependence within the last six months, as assessed by the MINI
•3. Known Diabetes Mellitus to exclude diabetic peripheral neuropathy
•4. History of coronary artery disease, hepatic disease, renal disease
•5. Other pain syndromes
•6. Any unstable medical conditions in the opinion of the investigator
•7. Other psychotropic medications excluding hypnotics

Locations (1)

Micheal E. DeBakey Veterans Hospital

Houston, Texas, United States

Key Dates

Start Date

January 1, 2007

Completion Date

June 1, 2007

Last Updated

August 12, 2022

Enrollment

ESTIMATED participants

Conditions

Chronic Phantom Limb Pain

Interventions

Duloxetine

DRUG