Clinical Trials in Florida

Showing 8801-8820 of 9,710 trials

Study Bendamustine Concurrent Whole Brain Radiation Brain Metastases From Solid Tumors

NCT00879073

The purpose of this study is to: * Test the maximum tolerated dose (MTD) of Bendamustine with whole brain radiation therapy (WBRT) * To determine the plasma pharmacokinetics (a blood test to see how much of the drug is getting into the patient's system and how long it lasts in the system) of Bendamustine * To determine the presence of Bendamustine in cerebrospinal fluid (CSF) (fluid from the brain and spinal cord) of study patients Bendamustine is approved by the Food and Drug Administration (FDA) for chronic lymphocytic leukemia. However, Bendamustine will be used in this study as an investigational agent.

Brain Metastases

H. Lee Moffitt Cancer Center and Research Institute12 participantsStarted Apr 2009

Tampa, Florida, United States

COMPLETEDPhase 249 miles

A 12-week Study of 4 Doses of VX-509 in Subjects With Active Rheumatoid Arthritis

NCT01052194

This study is designed to evaluate safety and assess initial efficacy of VX-509, a JAK3 inhibitor, for treatment of subjects with active RA. This study will assess the clinical response of 4 doses of VX-509 compared to placebo when administered for 12 weeks to patients with active RA. The study will also evaluate the safety and tolerability of VX-509 compared to placebo when administered for 12 weeks to subjects with active RA.

Rheumatoid Arthritis

Vertex Pharmaceuticals Incorporated206 participantsStarted Feb 2010

Birmingham, Alabama, United States • Huntsville, Alabama, United States • Peoria, Arizona, United States +45 more locations

Study Bendamustine Concurrent Whole Brain Radiation Brain Metastases From Solid Tumors

A 12-week Study of 4 Doses of VX-509 in Subjects With Active Rheumatoid Arthritis

Find Trials by Condition in Florida

Safety and Efficacy of Once-daily Oral Administrations of TZP-102 for Gastroparesis in Patients With Diabetes Mellitus

Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Women With Metastatic Breast Cancer

Brain Fitness in Parkinson's Disease

Phase I/II Safety Study of IPI-504 in Relapsed/Refractory Stage IIIb, or Stage IV Non-small Cell Lung Cancer (NSCLC)

Solifenacin Succinate (VESIcare) for the Treatment of Urinary Incontinence in Parkinson's Disease

Fibromyalgia Health Outcome Study on Cost of Treatments

Olanzapine Given in Combination With Zonisamide SR to Prevent Weight Gain in Schizophrenic Subjects

Study of Lornoxicam or Placebo for Acute Treatment of the Headache of Migraine.

Immunogenicity of a Split, Cell-Based, Inactivated, Trivalent Influenza Vaccine in Healthy Adult Subjects

A Study of the Effects of RoActemra/Actemra on Vaccination in Patients With Rheumatoid Arthritis on Background Methotrexate (VISARA)

The Efficacy and Safety of Degarelix One Month Dosing Regimens in Prostate Cancer

Trial of Three Neonatal Antiretroviral Regimens for Prevention of Intrapartum HIV Transmission

Efficacy and Safety of IPI-504 With Trastuzumab Pretreated, Locally Advanced or Metastatic HER2 Positive Breast Cancer

Effectiveness and Safety of 3 Dosing Regimens of CP-690,550 to Placebo in Subjects With Moderate to Severe Chronic Plaque Psoriasis

Study of Acid Reflux in Asthma

Xpress Digital Mammography System Images for Computer Aided Detection Development

Screening for Early Evidence of Diabetes

A Safety and Efficacy Study of Two Japanese Encephalitis Vaccines ChimeriVax™-JE and JE-VAX