Clinical Trials in Detroit

Showing 1521-1540 of 9,449 trials

A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

NCT06874335

This is a Phase 1, first in human (FIH), open-label, multicenter study of BHV-1530 in adult participants with advanced or metastatic solid tumors.

Solid Tumor

Biohaven Therapeutics Ltd.95 participantsStarted Mar 2025

Denver, Colorado, United States • Lake Mary, Florida, United States • Detroit, Michigan, United States +9 more locations

RECRUITINGPhase 1/2< 1 mile

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

NCT05887492

The goal of this interventional clinical trial is to learn about TNG260, a CoREST inhibitor, in combination with pembrolizumab in patients with advanced solid tumors with a known STK11 mutation. The main question\[s\] it aims to answer are: * the recommended dose for Phase 2 * to evaluate the safety and tolerability of the combination therapy * to determine the pharmacokinetics of TNG260 * to evaluate the initial antineoplastic activity Participants will receive study treatment until they experience an undesirable side effect, their disease progresses or until they withdraw consent.

Non Small Cell Lung CancerSolid Tumors, AdultLung Cancer+1 more

Tango Therapeutics, Inc.126 participantsStarted Jun 2023

Santa Monica, California, United States • Denver, Colorado, United States • Sarasota, Florida, United States +10 more locations

A Phase 1 Study of BHV-1530 in Advanced Solid Tumors

Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors

Find Trials by Condition in Detroit

Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031

Study BT5528-100 in Patients With Advanced Solid Tumors Associated With EphA2 Expression

Diagnostic and Therapeutic Applications of Microarrays in Liver Transplantation

A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of a New Formulation of Cabotegravir Long-Acting Administered Intramuscularly in a 4-month Dosing Interval (Q4M)

Study of Single Oral Doses of HOPO 14-1 Evaluating Safety, Tolerability, Pharmacokinetics

Utilizing CT Based Imaging Parameters of Body Composition to Understand Heterogeneity of Response to Biologic Therapies in Severe Asthma Cohorts

LowSalt4Life: A Mobile Application to Reduce Sodium Intake And Blood Pressure

Study of Safety and Efficacy of RGT-61159 in Adults With Relapsed/Refractory Adenoid Cystic Carcinoma (ACC) or Colorectal Carcinoma (CRC)

A Study to Investigate the Long-Term Safety of ZX008 (Fenfluramine Hydrochloride) Oral Solution in Children and Adults With Epileptic Encephalopathy Including Dravet Syndrome and Lennox-Gastaut Syndrome

Darbepoetin Trial to Improve Red Cell Mass and Neuroprotection in Preterm Infants

Clinical Trial of SOT102 Antibody Drug Conjugate in Patients With Advanced Gastric and Pancreatic Adenocarcinoma

Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease

An Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung Cancer

A Study to Assess the Efficacy, Safety and Tolerability of Different Doses of AZD0780 in Patients With Dyslipidemia

MARGetuximab Or Trastuzumab (MARGOT)

Confirmatory Study of Topical HyBryte™ vs. Placebo for the Treatment of CTCL

A Study to Evaluate the Efficacy and Safety of Pemigatinib (INCB054828) in Subjects With Myeloid/Lymphoid Neoplasms With FGFR1 Rearrangement - (FIGHT-203)

Natural History Study Protocol in PMM2-CDG (CDG-Ia)