Clinical Trials in Detroit

Showing 12141-12160 of 16,931 trials

An Open Label Study to Examine the Effects of a High-Fat Meal and Particle Size on the Pharmacokinetics of Orally Administered GSK2118436 in Subjects With BRAF Mutation Positive Tumor

NCT01231568

The study is designed to evaluate the effects of a high fat meal on the pharmacokinetics of 150 mg of GSK2118436, as well as the effects of particle size on the relative bioavailability of GSK2118436.

Cancer

GlaxoSmithKline28 participantsStarted Oct 2010

Scottsdale, Arizona, United States • Detroit, Michigan, United States • Nashville, Tennessee, United States +1 more locations

COMPLETEDPhase 1< 1 mile

VEG111485: A QTc Study of Pazopanib

NCT00861029

This is a Phase I, randomized, double-blind, placebo-controlled, study to estimate the effects of daily oral dosing of 800 mg pazopanib on electrocardiographic parameters (QTc interval duration) as compared with placebo in subjects with solid tumors. Moxifloxacin, will serve as a positive control.

Carcinoma, Renal Cell

GlaxoSmithKline2 participantsStarted Mar 2009

Duarte, California, United States • Santa Monica, California, United States • Detroit, Michigan, United States +5 more locations

An Open Label Study to Examine the Effects of a High-Fat Meal and Particle Size on the Pharmacokinetics of Orally Administered GSK2118436 in Subjects With BRAF Mutation Positive Tumor

VEG111485: A QTc Study of Pazopanib

Find Trials by Condition in Detroit

A Pharmacokinetics Study of the Effects of GSK2118436 on Warfarin, the Effects of Ketoconazole and Gemfibrozil on GSK2118436, and the Effects of Repeat Doses of GSK2118436 in Subjects With BRAF Mutant Solid Tumors

A Dose-Finding Study of GSK2894512 Cream in Subjects With Plaque Psoriasis

Single Dose Intravesical Apaziquone Postoperative in Patients Undergoing TURBT for Noninvasive Bladder Cancer (SPI-612)

Randomized Switch Study From Hydroxyurea to Ruxolitinib for RELIEF of Polycythemia Vera Symptoms: The Relief Study

Effectiveness of the Optifast Program Compared With a Reduced-energy Food Based Diet Plan on Body Weight

Management of Recurrent Croup

Carbon-11 Labeled Sarcosine in Prostate Cancer

TRX4 Monoclonal Antibody in Type 1 Diabetes (T1 DM)

Evaluating the Efficacy and Safety of Fluticasone Furoate Inhalation Powder in the Treatment of Asthma in Adults and Adolescents

Natural Evolution of AV Conduction Disorders in Patients Implanted With Cardiac Pacemakers

Pharmacokinetics And Pharmacodynamics Of Lapatinib In Two Dosing Regimens In Treatment-naive Patients With Breast Cancer

Safety and Tolerability Study of GSK1120212, a MEK Inhibitor, in Combination With Docetaxel, Erlotinib, Pemetrexed, Pemetrexed + Carboplatin, Pemetrexed + Cisplatin, or Nab-Paclitaxel

Extended Follow-Up After Islet Transplantation in T1D

Study of Dabrafenib +/- Trametinib in Combination With Ipilimumab for V600E/K Mutation Positive Metastatic or Unresectable Melanoma

A Phase IIIb Study to Evaluate the Efficacy of Umeclidinium/Vilanterol (UMEC/VI) in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

A Study of the GSK MEK Inhibitor GSK1120212 and Everolimus in Cancer Subjects

Study Of SB-497115 in Healthy Subjects and Subjects With Mild, Moderate or Severe Renal Impairment

Fractional Flow Reserve Versus Angiography for Multivessel Evaluation (F.A.M.E.)