Clinical Trials in Detroit

Showing 101-120 of 19,719 trials

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

NCT07213609

Solid tumours are abnormal lumps of tissue that can occur in different parts of the body. The tumours involved in this study have specific genetic characteristics that can make them more aggressive and challenging to treat. The study will test whether GSK5460025 alone or in combination (potential combinations may be included in future amendments to the protocol) with other anti-cancer agents can decrease tumor size, is safe, well-tolerated, and how the drug is processed in the body over time.

Neoplasms, ColorectalNeoplasms

GlaxoSmithKline47 participantsStarted Oct 2025

Aurora, Colorado, United States • Detroit, Michigan, United States • Canton, Ohio, United States +16 more locations

TERMINATEDPhase 1< 1 mile

A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2

NCT05514717

A Study of XMT-2056 in advanced/recurrent solid tumors that express HER2.

HER2-positive Breast CancerHER2-positive Gastric CancerHER2-positive Non-Small Cell Lung Cancer+3 more

Day One Biopharmaceuticals, Inc.57 participantsStarted Jan 2023

Los Angeles, California, United States • Los Angeles, California, United States • Stanford, California, United States +11 more locations

A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid Tumors

A Study of XMT-2056 in Advanced/Recurrent Solid Tumors That Express HER2

Find Trials by Condition in Detroit

To Evaluate if Green Tea Can be Effective in Reducing the Progression of Prostate Cancer in Men on Close Monitoring

Using Biomarkers to Help Guide Safe Immunotherapy Discontinuation in Patients With Unresectable Stage IIIB-IV Melanoma, The PET-Stop Trial

Rituximab With or Without Stem Cell Transplant in Treating Patients With Minimal Residual Disease-Negative Mantle Cell Lymphoma in First Complete Remission

Multiparametric MRI in Evaluating Cancer Stage and Helping Treatment Planning in Patients With Prostate Cancer

A Study to Evaluate Avacopan in Participants With ANCA-associated Vasculitis

Digital Tomosynthesis Mammography and Digital Mammography in Screening Patients for Breast Cancer

Abiraterone Acetate and Antiandrogen Therapy With or Without Cabazitaxel and Prednisone in Treating Patients With Metastatic, Castration-Resistant Prostate Cancer Previously Treated With Docetaxel

COVID-19 Related Financial Hardship and Distress in Women Who Decline TMIST (EA1151) Participation

A Study of Telitacicept for the Treatment of Generalized Myasthenia Gravis (UPSTREAM MG)

A Double-blind, Randomized Controlled Trial to Investigate the Efficacy, Safety, and Pharmacokinetics of Pegloticase Administration Via Subcutaneous and Intravenous Routes Both With Methotrexate in Participants With Uncontrolled Gout

A Study of Lebrikizumab (LY3650150) in Participants With Chronic Rhinosinusitis and Nasal Polyps Treated With Intranasal Corticosteroids (CONTRAST-NP)

A Study of CRLX101(NLG207) in Combination With Weekly Paclitaxel in Patients With Recurrent or Persistent Epithelial Ovarian, Fallopian Tube or Primary Peritoneal Cancer

A Clinical Trial That Will Study the Efficacy and Safety of an Investigational Drug in Acutely Psychotic People With Schizophrenia

Efficacy and Safety Study of TPX-115 on Partial-thickness Rotator Cuff Tear

Venetoclax-Dexamethasone in Relapsed and/or Refractory t(11;14) Amyloidosis

Efficacy and Safety of KAI-9531 in Participants Living With Obesity or Overweight With Weight-Related Comorbidities Who Do Not Have Diabetes

Cognitive Aftereffects of Neurotoxicity in Children and Young Adults With Relapsed/Refractory Hematologic Malignancies Who Receive CAR T-cell Therapy

A Study of WIN378 in Participants With Moderate to Severe COPD (Sirius)