Clinical Trials in Detroit

Showing 11121-11140 of 16,931 trials

Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma

NCT00404248

RATIONALE: Drugs used in chemotherapy, such as tetra-O-methyl nordihydroguaiaretic acid (EM-1421), work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. PURPOSE: This phase I/II trial is studying the side effects and best dose of EM-1421 and to see how well it works in treating patients with recurrent high-grade glioma.

Brain and Central Nervous System Tumors

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins35 participantsStarted Jan 2007

Birmingham, Alabama, United States • Tampa, Florida, United States • Atlanta, Georgia, United States +6 more locations

COMPLETEDPhase 3< 1 mile

Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy

NCT02607800

The primary objectives of this study are to compare the efficacy, safety, and tolerability of treatment with sofosbuvir/velpatasvir/voxilaprevir (SOF/VEL/VOX) fixed dose combination (FDC) for 8 weeks with that of SOF/VEL FDC for 12 weeks in direct-acting antiviral-naive participants with chronic hepatitis C virus (HCV) infection.

Hepatitis C

Gilead Sciences943 participantsStarted Nov 2015

Long Beach, California, United States • Los Angeles, California, United States • Palo Alto, California, United States +90 more locations

Tetra-O-Methyl Nordihydroguaiaretic Acid in Treating Patients With Recurrent High-Grade Glioma

Safety and Efficacy of Sofosbuvir/Velpatasvir/Voxilaprevir and Sofosbuvir/Velpatasvir in Adults With Chronic HCV Infection Who Have Not Previously Received Treatment With Direct-Acting Antiviral Therapy

Find Trials by Condition in Detroit

VL-2397 Compared to Standard First-Line Treatment for Invasive Aspergillosis (IA) in Adults

Model 4965 Post-Approval Study

Post Approval Study of the TS Feature With the 530G Pump System Supplemented With Commercial Patient Data

Comprehensive Opioid Management in Patient Aligned Care Teams

Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Heart Function in People Receiving an LVAD

Functional Remediation for Bipolar Disorder

Comparative Investigation of Low Molecular Weight (LMW) Heparin/Edoxaban Tosylate (DU176b) Versus (LMW) Heparin/Warfarin in the Treatment of Symptomatic Deep-Vein Blood Clots and/or Lung Blood Clots. (The Edoxaban Hokusai-VTE Study).

Naltrexone for Use in Conjunction With Buprenorphine in Adults With Opioid Use Disorder Prior to First Dose of VIVITROL® (Naltrexone for Extended-Release Injectable Suspension)

A Study to Evaluate ITCA 650 for the Treatment of Type 2 Diabetes in Patients With High Baseline HbA1c

ExAblate UF V2 System for the Treatment of Symptomatic Uterine Fibroids

Inflammation and the Host Response to Injury (Trauma)

Evaluation of a Single Vaccination With One of Three Ascending Dose Levels of a 4-Antigen Staphylococcus Aureus Vaccine (SA4Ag) in Healthy Adults Aged 18 to <65 Years

Multicenter Benchmarking of Functional and Psychosocial Outcomes of Pediatric Burn Survivors

Project LIFT - Promoting Healthy Behavior Through a Wearable Fitness Device and Financial Incentives

Safety and Efficacy Study of Herpes Simplex Virus Type 2 (HSV-2) Therapeutic DNA Vaccine

Safety and Efficacy Trial of DNA Vaccines to Treat Genital Herpes in Adults

An Open-Label Safety Study of API 31510 in a Topical Cream for in Situ Cutaneous Squamous Cell Carcinoma (SCCIS)

Long-term Follow-up Study of Subjects Who Completed Clinical Studies 755.1100_FA, 810.1100_FA, or 1064.1100_FA