Clinical Trials in Detroit

Showing 10501-10520 of 19,719 trials

Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases

NCT01461265

This study will evaluate the safety and efficacy of cryoablation therapy for relief of pain associated with metastatic bone tumors.

PainNeoplasm Metastasis

Boston Scientific Corporation29 participantsStarted Nov 2011

Detroit, Michigan, United States • Houston, Texas, United States • Vancouver, British Columbia, Canada +1 more locations

TERMINATEDPhase 22.6 miles

Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

NCT03345407

Nemiralisib is being developed as an anti-inflammatory drug for the treatment of inflammatory airways disease. This study is designed to assess the dose response, efficacy, safety, and pharmacokinetics of nemiralisib across a range of doses \[up to 750 micrograms (µg)\] compared with placebo. The study consists of a Screening Period, a 12-Week Treatment Period and a 12-Week Post-Treatment Follow-Up Period. Approximately 1,250 subjects with an acute moderate or severe exacerbation of COPD requiring standard of care (SoC) therapy will be randomized in this double-blind study. Subjects will be randomized to receive different doses of nemiralisib or placebo via ELLIPTA® inhaler. The total duration of study participation is approximately 6 months (170 days). ELLIPTA is the registered trademark of GlaxoSmithKline (GSK) group of companies.

Pulmonary Disease, Chronic Obstructive

GlaxoSmithKline943 participantsStarted Nov 2017

Mobile, Alabama, United States • Colorado Springs, Colorado, United States • Daytona Beach, Florida, United States +158 more locations

Safety and Efficacy of Cryoablation for the Palliation of Painful Bone Metastases

Dose Finding Study of Nemiralisib (GSK2269557) in Subjects With an Acute Moderate or Severe Exacerbation of Chronic Obstructive Pulmonary Disease (COPD)

Find Trials by Condition in Detroit

Trial of Extended Release Bupivacaine for Pain Relief After Surgery

Safety and Efficacy Study of GRT6005 in Patients With Osteoarthritis (OA) Knee Pain

Efficacy and Safety of LBH589B in Adult Patients With Refractory Chronic Myeloid Leukemia in Accelerated or Blast Phase

Healthy Term Infants Fed Milk-Based Infant Formula

Study to Prevent Acute Kidney Injury After Cardiac Surgery Involving Cardiopulmonary Bypass

Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects

A Long Term Study of ALKS 5461 in the Treatment of Refractory Major Depressive Disorder (MDD)

A Comparative Study Between Fluticasone Furoate/Umeclidinium/Vilanterol (FF/UMEC/VI) Single Inhaler Triple Therapy Versus Tiotropium Monotherapy in Subjects With Chronic Obstructive Pulmonary Disease (COPD)

StrataGraft® Skin Tissue in the Promotion of Autologous Skin Regeneration of Complex Skin Defects Due to Thermal Burns That Contain Intact Dermal Elements

Alglucosidase Alfa Pompe Safety Sub-Registry

Dose Response of 28 Days of Dosing of GSK962040 in Type I and II Diabetic Male and Female Subjects With Gastroparesis

Study to Investigate Safety, Pharmacokinetic (PK), Pharmacodynamic (PD) and Clinical Activity of Trametinib in Subjects With Cancer or Plexiform Neurofibromas and Trametinib in Combination With Dabrafenib in Subjects With Cancers Harboring V600 Mutations

Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study In Subjects With Osteoarthritic Pain Of The Knee

Safety and Acceptability of Deferiprone Delayed Release Tablets in Patients With Systemic Iron Overload

Dose Escalation Study of AST-OPC1 in Spinal Cord Injury

NeoMend ProGEL™ Pleural Air Leak Sealant Post-Approval Study

Cebranopadol Efficacy and Safety in Diabetic Patients Suffering From Chronic Pain Caused by Damage to the Nerves

Safety, Tolerability, and Efficacy of Monotherapy and Combination Regimens in Participants With Nonalcoholic Steatohepatitis (NASH)