Clinical Trials in Detroit

Showing 9781-9800 of 19,719 trials

OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

NCT03180307

This is a phase 3, randomized, multi-center, single dose, open label, pivotal study in patients diagnosed with, or with high clinical suspicion of, ovarian cancer scheduled to undergo primary surgical cytoreduction, interval debulking, or recurrent ovarian cancer surgery.

Ovarian Cancer

On Target Laboratories, LLC140 participantsStarted Jan 2018

Phoenix, Arizona, United States • Tucson, Arizona, United States • Duarte, California, United States +8 more locations

TERMINATEDPhase 1< 1 mile

Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias

NCT03761069

This is an open-label, non-randomized, Phase 1b study to evaluate the safety, pharmacokinetics (PK) profiles, and preliminary evidence of antitumor activity of PTC299 and the metabolite, O-desmethyl PTC299, in participants with relapsed/refractory acute myeloid leukemia (AML) who have exhausted standard available therapies known to provide clinical benefit. The study is designed as a series of cohort-based dose escalations. For each cohort, a minimum of 3 evaluable participants with PK and safety data will be assessed. Additional participants will be recruited if additional PK data are needed to assess mean exposure based on the observed variability.

Leukemia, Myeloid, AcuteAML

PTC Therapeutics33 participantsStarted Oct 2018

Aurora, Colorado, United States • New Haven, Connecticut, United States • Detroit, Michigan, United States +14 more locations

OTL38 for Intra-operative Imaging of Folate Receptor Positive Ovarian Cancer

Study of PTC299 (Emvododstat) in Relapsed/Refractory Acute Leukemias

Find Trials by Condition in Detroit

Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis

Combination Chemotherapy in Treating Young Patients With Down Syndrome and Acute Myeloid Leukemia or Myelodysplastic Syndromes

Efficacy Evaluation of Products Against Long Wavelength Ultraviolet A1 and Visible Light Induced Biological Effects

Long-Term Safety and Efficacy of Repeat Treatments of DaxibotulinumtoxinA for Injection in Adults With Isolated Cervical Dystonia (ASPEN-OLS)

SUSTAIN SWITCH: A Research Study to Compare Two Dose Schedules of Semaglutide Taken Once Weekly in People With Type 2 Diabetes

Tolperisone in Acute Muscle Spasm of the Back

Minocycline Hydrochloride in Reducing Chemotherapy-Induced Peripheral Neuropathy and Acute Pain in Patients With Breast Cancer Undergoing Treatment With Paclitaxel

Clinical Evaluation of a Daily Wear Silicone Hydrogel Lens

Lenalidomide in Treating Patients With AIDS-Associated Kaposi's Sarcoma

Phase I/Ib Study of NIS793 in Combination With PDR001 in Patients With Advanced Malignancies.

Safety and Efficacy Study of Adult Human Mesenchymal Stem Cells to Treat Acute Graft Versus Host Disease (GVHD)

Safety Study of Enoblituzumab (MGA271) in Combination With Ipilimumab in Refractory Cancer

Feasibility of Telemedicine Medical Abortion

Enoblituzumab (MGA271) in Children With B7-H3-expressing Solid Tumors

Veliparib (ABT-888), an Oral PARP Inhibitor, and VX-970, an ATR Inhibitor, in Combination With Cisplatin in People With Refractory Solid Tumors

Active Limb Orthosis for Home-Use Stroke Hemiparetic Gait Rehabilitation

Study to Determine Safety and Dose of NJH395 in Non-breast HER2+ Advanced Cancer

Awareness, Care & Treatment In Obesity Management - An International Observation Among Teens (ACTION Teens)