Clinical Trials in Detroit

Showing 5941-5960 of 14,997 trials

Immuno-regulatory Profiling of T Cells in GVHD Treated With Extracorporeal Photopheresis

NCT03851601

Extracorporeal Photopheresis (ECP) has been used as one of the treatments for graft versus host disease (GVHD). Responses were observed in skin, liver, GI tract, mouth, eye and lung. ECP does not cause immune suppression and therefore less risk of infection or relapse of malignancy. However, the exact mechanism of action of this expensive procedure is not fully understood and no predictors of response to ECP are known so far. This reflects the need for a better understanding of GVHD and its response to ECP. Blood samples from 15 patients who receive ECP as part of the treatment of GVHD at our institution will be collected. Samples will be analyzed using flow cytometer

GVHD

Henry Ford Health System6 participantsStarted Aug 2014

Detroit, Michigan, United States

COMPLETEDPhase 2< 1 mile

Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

NCT02484443

This phase II trial studies how well dinutuximab works when given with sargramostim in treating patients with osteosarcoma that has come back after treatment (recurrent). Monoclonal antibodies, such as dinutuximab, may find tumor cells and help kill them. Sargramostim may help the body increase the amount of white blood cells it produces, which help the body fight off infections. Giving dinutuximab with sargramostim may work better and kill more cancer cells.

Metastatic Malignant Neoplasm in the LungMetastatic OsteosarcomaRecurrent Osteosarcoma

National Cancer Institute (NCI)41 participantsStarted Feb 2016

Birmingham, Alabama, United States • Phoenix, Arizona, United States • Little Rock, Arkansas, United States +127 more locations

Immuno-regulatory Profiling of T Cells in GVHD Treated With Extracorporeal Photopheresis

Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma

Find Trials by Condition in Detroit

Safety and Efficacy Study of AVB-S6-500 (Batiraxcept) in Patients With Advanced Pancreatic Adenocarcinoma

A Study to Compare the Efficacy of Arfolitixorin Versus Leucovorin in Combination With 5 Fluorouracil, Oxaliplatin, and Bevacizumab in Patients With Advanced Colorectal Cancer

Human Algorithm Interactions for Acute Respiratory Failure Diagnosis

Neural Mechanisms of Mindfulness-based Cognitive Therapy (MBCT) for Posttraumatic Stress Disorder (PTSD)_VA Only

Trial of Pevonedistat Plus Docetaxel in Patients With Previously Treated Advanced Non-Small Cell Lung Cancer

Flecainide Acetate Inhalation Solution for Cardioversion of Recent-Onset, Symptomatic Atrial Fibrillation

Study to Assess the Safety and Efficacy of Ribociclib (LEE011) in Combination With Letrozole for the Treatment of Men and Pre/Postmenopausal Women With HR+ HER2- aBC

Multi-Center Study to Evaluate the ConforMIS iUni Knee Implant

A Prospective, Multicenter Study to Evaluate the ConforMIS iTotal® (CR) Knee Replacement System

A Study of HB0045 Injection in Patients With Advanced Solid Tumors

Study of the ConforMIS iDuo(R) G2

Developmental Impact of NICU Exposures (DINE)

A Study of mRNA-1010 Seasonal Influenza Vaccine in Healthy Adults

A Study to Evaluate the Safety and Tolerability of ABBV-951 in Subjects With Parkinson's Disease (PD)

ORACLE-NIRS: Lipid cORe Plaque Association With CLinical Events: a Near-InfraRed Spectroscopy Study

A Prospective Study to Evaluate the ConforMIS iTotal® (PS) Knee Replacement System

A Study to Investigate Atezolizumab and Chemotherapy Compared With Placebo and Chemotherapy in the Neoadjuvant Setting in Participants With Early Stage Triple Negative Breast Cancer

Alignment Comparison Between TruMatch™ Personalized Solutions and Conventional Total Knee Replacement Instrumentation