Clinical Trials in Detroit

Showing 4081-4100 of 19,719 trials

Efficacy and Safety of Perampanel in the Treatment of Refractory Status Epilepticus

NCT05684978

This project is aiming to better understand the use of perampanel as an appropriate standard-of-care therapy for treatment refractory status epilepticus (RSE), to identify determinants of outcomes, and establish safety. The study will recruit 25 patients at WSU. The study will last for about 96 weeks and will involve a screening visit and two in clinic visits at 3 and 6 months. If the subjects give written informed consent and meet all eligibility criteria they will be clinically evaluated and will be given the study drug. This study will involve recording of patients medical history, drug history and epilepsy history. A physical exam and a and neurological exam will also be performed to study the heath status of the participant. Results and patient information will be stored in a database for analysis to find commonality among key factors that have been seen in past research.

Refractory Status Epilepticus

Wayne State University1 participantsStarted Oct 2025

Detroit, Michigan, United States

COMPLETEDPhase 2/3< 1 mile

Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study

NCT04887870

A Study of Sitravatinib Alone or in Combination with Other Anticancer Therapies in Advanced or Metastatic Malignancies

Advanced or Metastatic Solid Malignancies

Mirati Therapeutics Inc.52 participantsStarted Jun 2021

Littleton, Colorado, United States • Goshen, Indiana, United States • Boston, Massachusetts, United States +10 more locations

Efficacy and Safety of Perampanel in the Treatment of Refractory Status Epilepticus

Study of Sitravatinib With or Without Other Anticancer Therapies Receiving Clinical Benefit From Parent Study

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ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)

Effects of Myofascial Massage and Patient-therapist Communication Levels on Shoulder Muscle Properties in Breast Cancer Survivors With Myofascial Pain

Multi-Center Clean Air Randomized Controlled Trial in COPD

Safety and Efficacy of Nyxol With Pilocarpine Eye Drops in Subjects With Presbyopia

Prospective Clinical Assessment Study in Children With Hypochondroplasia

A Clinical Study That Will Measure How Well SEP-363856 Works and How Safe it is in Adults With Generalized Anxiety Disorder

Interferon-γ (IFN-γ) With Donor Leukocyte Infusion to Treat Relapsed Acute Myeloid Leukemia and Myelodysplastic Syndromes Post Allogeneic Hematopoietic Stem Cell Transplantation

RNA Disruption Assay (RDA)-Breast Cancer Response Evaluation for Individualized Therapy

Study to Compare Bictegravir/Lenacapavir Versus Current Therapy in People With HIV-1 Who Are Successfully Treated With a Complicated Regimen

Natural History of Netherton Syndrome

Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment

Effects of Long-Duration Spaceflight on General and Spatial Cognition and Its Neural Basis

A Study of TLN-254 in Participants With Relapsed or Refractory T-cell Lymphoma

Study to Investigate the Safety and Tolerability of Odronextamab in Patients With CD20+ B-Cell Malignancies

Study of Efficacy and Safety of Ribociclib (LEE011) in Combination With Topotecan and Temozolomide (TOTEM) in Pediatric Patients With Relapsed or Refractory Neuroblastoma and Other Solid Tumors

A Study to Learn About the Occurrence of ADHD in Adults With Mental Conditions and Their Quality of Life

Ultrasound Stimulation for Patients in a Disorder of Consciousness