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An Open-Label, Multicenter Extension and Long-Term Observational Study in Patients Previously Enrolled in a Genentech- and/or F. Hoffmann-La Roche Ltd-Sponsored Atezolizumab Study
This is an open-label, multicenter, non-randomized extension and long-term observational study. Participants receiving atezolizumab monotherapy or atezolizumab combined with other agent(s) or comparator agent(s) in a Genentech or Roche-sponsored study (the parent study) and who continue to receive study treatment at the time of the parent-study closure and do not have access to the study treatment locally are eligible for continued treatment in the extension study. Dosing regimen for a given participant and indication will be the same or equivalent to the respective parent study protocol. Study treatment in the extension study can continue until disease progression or beyond if the patient continues to derive clinical benefit as judged by the investigator and if allowed by the parent study or local prescribing information until death; withdrawal of study consent; unacceptable toxicity; pregnancy; patient non-compliance; or study termination by the Sponsor, whichever occurs first.
Age
All ages
Sex
ALL
Healthy Volunteers
No
HonorHealth Research Institute ? Bisgrove
Scottsdale, Arizona, United States
Angeles Clinic & Rsch Inst
Los Angeles, California, United States
UCLA
Los Angeles, California, United States
Kaiser Permanente - San Diego (Zion Ave)
San Marcos, California, United States
University Of Colorado
Aurora, Colorado, United States
Rocky Mountain Cancer Ctr - Denver (Williams)
Denver, Colorado, United States
Smilow Cancer Hospital at Yale New Haven
New Haven, Connecticut, United States
Georgetown University Medical Center Lombardi Cancer Center
Washington D.C., District of Columbia, United States
Florida Cancer Specialists - Fort Myers (Broadway)
Fort Myers, Florida, United States
Hematology Oncology Associates of the Treasure Coast
Port Saint Lucie, Florida, United States
Start Date
September 20, 2017
Primary Completion Date
March 6, 2030
Completion Date
March 6, 2030
Last Updated
January 13, 2026
382
ACTUAL participants
Atezolizumab
DRUG
Bevacizumab
DRUG
Lead Sponsor
Hoffmann-La Roche
NCT05673200
NCT05691465
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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