Clinical Trials in Detroit

Showing 2521-2540 of 9,449 trials

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

NCT05757492

This phase 1 open-label study will evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of CHS-006 in combination with toripalimab in 2 phases. Phase 1 (Dose Optimization phase) will explore 2 different dose combinations in participants with advanced/metastatic solid tumors (except pancreatic) and Phase 2 (Indication-specific Expansion phase) will use one selected dose in specific tumor types (non-small cell lung cancer-non squamous \[NSCLC-NS\] and Hepatocellular carcinoma \[HCC\])

Advanced Solid TumorNon-Small Cell Lung CancerHepatocellular Carcinoma

Coherus Oncology, Inc.22 participantsStarted Apr 2023

Orlando, Florida, United States • Detroit, Michigan, United States • Reno, Nevada, United States +1 more locations

RECRUITINGNA12 miles

AltaValve Pivotal Trial

NCT06465745

This is a prospective, single arm, multicenter, clinical trial designed to evaluate the safety and performance of the AltaValve System for the treatment of mitral regurgitation in a targeted patient population.

Mitral RegurgitationMitral InsufficiencyMitral Valve Incompetence+2 more

4C Medical Technologies, Inc.450 participantsStarted Sep 2024

Phoenix, Arizona, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +26 more locations

Study to Evaluate Safety and PK of CHS-006 in Combination With Toripalimab in Patients With Advanced Solid Tumors

AltaValve Pivotal Trial

Find Trials by Condition in Detroit

Precision-T: A Study of Orca-T in Recipients Undergoing Allogeneic Transplantation for Hematologic Malignancies

Chronic Pain in Rheumatoid Arthritis

An Efficacy and Safety Study of Sirukumab in Participants With Major Depressive Disorder

A Phase III, Crossover Trial Evaluating the Efficacy and Safety of KVD900 (Sebetralstat) for On-Demand Treatment of Angioedema Attacks in Adolescent and Adult Patients With Hereditary Angioedema (HAE)

Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone

A Study Comparing Daratumumab, Lenalidomide, and Dexamethasone With Lenalidomide and Dexamethasone in Relapsed or Refractory Multiple Myeloma

Study of Dabrafenib+Trametinib in the Adjuvant Treatment of Stage III BRAF V600+ Melanoma After Complete Resection to Evaluate the Impact on Pyrexia Related Outcomes

Post Approval Study of Liposorber LA-15 System for the Treatment of Focal Segmental Glomerulosclerosis in Children

A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy

ShOrt neCK AAA RAndomized Trial - ESAR and FEVAR: SOCRATES

The ENERGY 3 Study: Evaluation of Efficacy and Safety of INZ-701 in Children With ENPP1 Deficiency

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression

A Study of Carfilzomib, Lenalidomide, Dexamethasone and Daratumumab for Patients With Relapsed/Refractory Myeloma With Salvage Autologous Hematopoietic Cell Transplantation

A Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sjögren's Syndrome

Promoting Early Intervention Timing and Attention to Language

A Digital Intervention to Improve Physical Activity and Sleep Behaviors in Youth With Psychiatric Diagnoses

A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)

An Investigation to Validate Speech Perception Assessment for Adult Cochlear Recipients Using a Mobile Research App