Clinical Trials in Denver

Showing 6781-6800 of 18,161 trials

Adaptation of Insulin Delivery Settings to Improve Clinical Outcomes With AID Use

NCT05204134

Obtain preliminary safety and performance data on a settings initialization and adaptation algorithm used in conjunction with closed-loop control.

Type 1 Diabetes

Tandem Diabetes Care, Inc.33 participantsStarted Mar 2022

Aurora, Colorado, United States

Active Not RecruitingPhase 28.4 miles

A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts

NCT02266745

This is a Phase 1/2, open-label, multi-center, non-randomized, dose-escalation study to be conducted in two parts: the Dose Escalation Phase and the Dose Expansion Phase. The Dose Escalation Phase will determine the Maximum Tolerated Dose (MTD) and recommended Phase 2 dose(s) (RP2D) of PT-112 Injection and evaluate its safety and tolerability, and PK (pharmacokinetics). The Dose Escalation Phase is complete and no longer enrolling. The Dose Expansion Phase has two cohorts: one cohort for the study of PT-112 in patients with thymoma and thymic carcinoma (Cohort A), and one cohort for the study of PT-112 in metastatic castrate-resistant prostate cancer (mCRPC) (Cohort D).

Advanced Solid TumorsCRPCmCRPC+6 more

Promontory Therapeutics Inc.109 participantsStarted Jul 2014

Phoenix, Arizona, United States • Tucson, Arizona, United States • Duarte, California, United States +22 more locations

Adaptation of Insulin Delivery Settings to Improve Clinical Outcomes With AID Use

A Study Evaluating the Safety, Pharmacokinetics, and Clinical Effects of Intravenously Administered PT-112 Injection in Subjects With Advanced Solid Tumors and Subsequent Dose Expansion Cohorts

Find Trials by Condition in Denver

Palbociclib (PD-0332991) Combined With Fulvestrant In Hormone Receptor+ HER2-Negative Metastatic Breast Cancer After Endocrine Failure (PALOMA-3)

Phase 3 Randomized, Double-blind, Controlled Study of ICT-107 in Glioblastoma

Longitudinal Innate Immunity and Aging Study

An Evaluation of the Efficacy and Safety of CSF-1 in the Temporary Correction of Presbyopia (NEAR-2)

Philps FAST2022 picoSAT Pulse Oximetry Desaturation Study

An Open-Label, Single Arm Study of Obinutuzumab Short Duration Infusion in Patients With Previously Untreated Advanced Follicular Lymphoma

Feasibility of Reducing Cardiovascular Disease Risk Factors in Hispanics Through a Family-Based Community Intervention

Study to Compare the Efficacy and Safety of Enzyme Replacement Therapies Avalglucosidase Alfa and Alglucosidase Alfa Administered Every Other Week in Patients With Late-onset Pompe Disease Who Have Not Been Previously Treated for Pompe Disease

Carisbamate Safety Study in Adult and Pediatric Subjects With Lennox-Gastaut Syndrome

Treatment Effects of Subcutaneous Injections of Pentosan Polysulfate Sodium vs Placebo in Participants With Knee OA Pain

Spiration Valves Against Standard Therapy

Study of AT-02 in Healthy Volunteers and Subjects With Systemic Amyloidosis

TAC/MTX vs. TAC/MMF/PTCY for Prevention of Graft-versus-Host Disease and Microbiome and Immune Reconstitution Study (BMT CTN 1703/1801)

Study to Evaluate Safety, PK, PD, Immunogenicity & Antitumor Activity of MSC-1 in Patients With Adv Solid Tumors

Study of Edecesertib in Participants With Cutaneous Lupus Erythematosus (CLE)

Phase 2a Study of CAN-2409 With Standard Radiation Therapy for Malignant Glioma

An Investigation of the Metal Concentration in Patients Implanted With the PRESTIGE LP™ Cervical Disc at Two Contiguous Levels in the Cervical Spine

A Study of Atezolizumab in Locally Advanced or Metastatic Urothelial or Non-Urothelial Carcinoma of the Urinary Tract