Clinical Trials in Denver

Showing 5101-5120 of 18,161 trials

Chronic Pain in Rheumatoid Arthritis

NCT05038553

The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been shown to be involved in chronic pain.

Arthritis, RheumatoidPain

Northwestern University125 participantsStarted Oct 2021

Denver, Colorado, United States • Chicago, Illinois, United States • Baltimore, Maryland, United States +2 more locations

TERMINATEDPhase 3< 1 mile

A Study of Ustekinumab in Participants With Active Systemic Lupus Erythematosus

NCT03517722

The purpose of this study is to evaluate the efficacy of ustekinumab in participants with active systemic lupus erythematosus (SLE) who have not adequately responded to one or more standard of care treatments.

Lupus Erythematosus, Systemic

Janssen Research & Development, LLC516 participantsStarted Apr 2018

Anniston, Alabama, United States • Birmingham, Alabama, United States • Vestavia Hills, Alabama, United States +201 more locations

Chronic Pain in Rheumatoid Arthritis

A Study of Ustekinumab in Participants With Active Systemic Lupus Erythematosus

Find Trials by Condition in Denver

A Study of Suboptimally Controlled Participants Previously Taking Injectable DMDs for RMS (CLICK-MS)

A Phase 1/2, First-in-Human Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Preliminary Efficacy of a Subretinal Injection of SB-007 in Subjects With Stargardt Disease (STGD1)

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

A Study to Evaluate the Safety and Efficacy of Ustekinumab Induction and Maintenance Therapy in Participants With Moderately to Severely Active Ulcerative Colitis

A Study to Evaluate Subcutaneous Daratumumab in Combination With Standard Multiple Myeloma Treatment Regimens

A Safety and Efficacy Study of JNJ26489112 in Patients With Treatment-Resistant Major Depressive Disorder

A Study of Seltorexant in Participants With Probable Alzheimer's Disease

A Study to Assess the Bioequivalence of Ustekinumab by Two Different Injection Devices in Healthy Participants

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant

54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide

Safety, Tolerability and Efficacy of ACZ885 on Leg Artery Structure in Patients With Peripheral Artery Disease

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

Pulmonary Hemodynamics During Exercise - Research Network

Azacitidine and Entinostat in Treating Patients With Advanced Breast Cancer

Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee Arthroplasty

A Study of Ustekinumab in Pediatric Participants (U-POPS) With Juvenile Psoriatic Arthritis or Psoriasis

A Study to Evaluate the Safety and Efficacy of Intranasal Esketamine in Treatment-resistant Depression

Study of Dabrafenib+Trametinib in the Adjuvant Treatment of Stage III BRAF V600+ Melanoma After Complete Resection to Evaluate the Impact on Pyrexia Related Outcomes