Clinical Trials in Denver

Showing 4821-4840 of 13,773 trials

Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization

NCT03942601

This is a prospective, multi-center, pilot feasibility study to document the effects of adventitial delivery of temsirolimus or temsirolimus with dexamethasone sodium phosphate injection, USP, after revascularization of femoropopliteal lesions in symptomatic patients with moderate to severe claudication (Rutherford 2-3) or critical limb ischemia (CLI) with rest pain (Rutherford 4). Subjects will be followed for up to 60 months post index procedure.

Peripheral Arterial Disease

Mercator MedSystems, Inc.10 participantsStarted Oct 2019

Little Rock, Arkansas, United States • Orange, California, United States • San Francisco, California, United States +8 more locations

COMPLETEDPhase 38.4 miles

Study of the Safety of HPN (Hyperion)-100 for the Long-Term Treatment of Urea Cycle Disorders (Treat UCD)

NCT00947297

This was a long-term safety study HPN-100 in urea cycle disorder (UCD) subjects. Subjects were assessed regularly for safety and control of their venous ammonia. Hyperammonemic events were characterized with respect to contributing factors, such as intercurrent illness, diet, and noncompliance with medication.

Urea Cycle Disorders

Amgen60 participantsStarted Nov 2009

Long Beach, California, United States • Los Angeles, California, United States • Stanford, California, United States +19 more locations

Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization

Study of the Safety of HPN (Hyperion)-100 for the Long-Term Treatment of Urea Cycle Disorders (Treat UCD)

Find Trials by Condition in Denver

Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease

A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD)

Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders

Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

Safety and Efficacy of Piromelatine in Mild Alzheimer's Disease Patients (ReCOGNITION)

A Study of the Safety, Efficacy, and Biomarker Response of BMS-986165 in Participants With Moderate to Severe Ulcerative Colitis

A Safety and Effectiveness Study of a New Preservative Free Rewetting Drop

Feasibility Study on LITT for Medical Refractory Epilepsy

Impact of Microvascular Inflammation on Kidney Allograft Outcome

Phase Ib/2, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Hepatocellular Carcinoma

Belimumab Assessment of Safety in SLE

Ambispective Clinical Evaluation of Sophono™

Leidos-Enabled Adaptive Protocol (LEAP-CT) for Evaluation of Post-exposure Prophylaxis for Newly-infected COVID-19 Patients

Safety and Efficacy of ARQ-252 Cream 0.3% in Subjects With Non-Segmental Facial Vitiligo

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Study of GSK3359609 and Pembrolizumab in Programmed Death Receptor 1-ligand 1 (PD-L1) Positive Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma

Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders

C-myc Biomarker Study for Diabetic Foot Ulcers