Fasting plasma glucose ≥ 126 mg/dl - participants will not be excluded if they an abnormal post prandial glucose levels (e.g. glucose ≥ 200 mg/dl) following the MTT's.
Tobacco use (cigarettes, cigars, or chewing tobacco) within the past 6 months
Females who previously used (\> 6 months) or are currently using any formulation of estrogen-based hormone therapy (e.g., oral Premarin, transdermal 17-estradiol, selective estrogen receptor modulators).
Resting diastolic blood pressure \> 100 mm mercury or resting systolic blood pressure \> 160 mm mercury
Contra-indications to exercise (e.g. orthopedic limitations)
Unable to walk on a treadmill for 36 continuous minutes at a pace of at least 2.0 mph
Clareo Health | Effects of Interrupting Sedentary Time on Glycemic Control in Older Overweight and Obese Adults