Clinical Trials in Denver

Showing 3001-3020 of 8,669 trials

Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization

NCT03942601

This is a prospective, multi-center, pilot feasibility study to document the effects of adventitial delivery of temsirolimus or temsirolimus with dexamethasone sodium phosphate injection, USP, after revascularization of femoropopliteal lesions in symptomatic patients with moderate to severe claudication (Rutherford 2-3) or critical limb ischemia (CLI) with rest pain (Rutherford 4). Subjects will be followed for up to 60 months post index procedure.

Peripheral Arterial Disease

Mercator MedSystems, Inc.10 participantsStarted Oct 2019

Little Rock, Arkansas, United States • Orange, California, United States • San Francisco, California, United States +8 more locations

COMPLETEDPhase 1/28.4 miles

Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors

NCT03320330

This phase I/II trial studies the side effects and best dose of pepinemab and to see how well it works in treating younger patients with solid tumors that have come back after treatment, or do not respond to treatment. Immunotherapy with monoclonal antibodies, such as pepinemab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.

Recurrent Malignant Solid NeoplasmRecurrent OsteosarcomaRefractory Malignant Solid Neoplasm+1 more

Children's Oncology Group26 participantsStarted Jan 2018

Birmingham, Alabama, United States • Los Angeles, California, United States • Orange, California, United States +21 more locations

Temsirolimus Alone or Paired With Dexamethasone Delivered to the Adventitia to eNhance Clinical Efficacy After Femoropopliteal Revascularization

Pepinemab in Treating Younger Patients With Recurrent, Relapsed, or Refractory Solid Tumors

Find Trials by Condition in Denver

Impact of HIV-1 and Aging on Mucosal Vaccine Responses

Filgotinib in Long-Term Extension Study of Adults With Crohn's Disease

A Study to Find Out How Nintedanib is Taken up in the Body and How Well it is Tolerated in Children and Adolescents With Interstitial Lung Disease (ILD)

Efficacy and Safety of HPN-100 for the Treatment of Adults With Urea Cycle Disorders

Effects of Pecan Nut Snacks v Equicaloric Snacks on Appetite, Food Intake, Metabolism, Hormones and Biomarkers

Study to Assess the Efficacy and Safety of Nemolizumab (CD14152) in Participants With Prurigo Nodularis (PN)

Acute Kidney Injury in Patients Undergoing Contrast Exposure: VQ vs. CT

Oral Nutritional Supplementation in Children at Risk of Undernutrition

A Study of the Safety, Efficacy, and Biomarker Response of BMS-986165 in Participants With Moderate to Severe Ulcerative Colitis

A Safety and Effectiveness Study of a New Preservative Free Rewetting Drop

Impact of Microvascular Inflammation on Kidney Allograft Outcome

Phase Ib/2, Multicenter, Dose Escalation Study of DCR-MYC in Patients With Hepatocellular Carcinoma

Belimumab Assessment of Safety in SLE

Safety and Efficacy of ARQ-252 Cream 0.3% in Subjects With Non-Segmental Facial Vitiligo

Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Safety of Repeat Intravitreal Injection of Human Retinal Progenitor Cells (jCell) in Adult Subjects With Retinitis Pigmentosa

Study of the Safety and Tolerability of HPN-100 Compared to Sodium Phenylbutyrate in Children With Urea Cycle Disorders

C-myc Biomarker Study for Diabetic Foot Ulcers