Clinical Trials in Dallas

Showing 14241-14260 of 17,468 trials

Study to Assess the Safety and Tolerability of Multiple Ascending Doses of REGN1500

NCT02107872

This is a phase 1, randomized, double-blind, placebo-controlled, multiple ascending dose study to assess the safety, tolerability, pharmacokinetic (PK), immunogenicity, and pharmacodynamic (PD) effects of REGN1500 in patients with a metabolic disorder.

Metabolic Disorders

Regeneron Pharmaceuticals55 participantsStarted Apr 2014

Daytona Beach, Florida, United States • Evansville, Indiana, United States • Dallas, Texas, United States +1 more locations

COMPLETEDPhase 3< 1 mile

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension

NCT00660179

The AC-055-302/SERAPHIN study will be an event-driven Phase III study, comparing two different doses of macitentan (ACT-064992) (3 and 10 mg) vs placebo in patients with symptomatic PAH. The main study objective is to demonstrate that macitentan (ACT-064992) prolongs time to the first morbidity or mortality event, and to evaluate the benefit/risk profile of macitentan (ACT-064992) in the treatment of patients with symptomatic PAH.

Pulmonary Arterial Hypertension

Actelion742 participantsStarted May 2008

Birmingham, Alabama, United States • Pheonix, Arizona, United States • Los Angeles, California, United States +150 more locations

Study to Assess the Safety and Tolerability of Multiple Ascending Doses of REGN1500

Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial Hypertension

Find Trials by Condition in Dallas

Baby Observational and Nutritional Study

Perindopril Amlodipine for the Treatment of Hypertension

Safety and Tolerability of Rituxan With Methotrexate and Etanercept or Methotrexate and Adalimumab in Patients With Active Rheumatoid Arthritis

Influenza Vaccine in Premature Infants

Evaluation of Dose-titration of Pramlintide During Initiation of Therapy in Patients Trying to Improve Glucose Control

Study to Assess the Efficacy and Safety of Three Dosage Strengths of Pulsatile GnRH Delivered From a Iontophoretic Patch Compared to Oral Treatment With Clomiphene or Placebo in Infertile Females

ch14.18 Pharmacokinetic Study in High-risk Neuroblastoma

Study of Ivacaftor in Cystic Fibrosis Subjects Aged 12 Years and Older Homozygous for the F508del-CFTR Mutation

The Evaluation of Cow Milk-Based Formulas

Safety and Efficacy Study of Photodynamic Therapy With Levulan Kerastick + Blue Light for Actinic Keratoses on the Upper Extremities

Safety and Toleration of PEP005 Topical Gel When Applied to a Treatment Area of up to 100cm2

Study of the Safety and Efficacy of REGN727/SAR236553 in Patients With HeFH Hypercholesterolemia

BG00010 (Neublastin) Phase 2 Multiple Dose Adaptive Design in Participants With Painful Lumbar Radiculopathy

A Study of Combination Thalidomide Plus Dexamethasone Therapy vs. Dexamethasone Therapy Alone in Previously Untreated Subjects With Multiple Myeloma

Treatment of HER2-Positive Metastatic Breast Cancer With Herceptin and Bevacizumab (Antibodies Against HER2 and VEGF)

Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) When Co-administered With High Dose of Atorvastatin in Patients With Primary Hypercholesterolemia

AMG386 Comb w. Either Pegylated Liposomal Doxorubicin or Topotecan Subjects w. Advanced Recurrent Epithelial Ovarian CR

Effect of Denosumab on Cellular Biomarkers in the Human Breast