Clinical Trials in Dallas

Showing 4881-4900 of 17,468 trials

Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF

NCT05723679

The overall purpose of this study is to investigate whether pulmonary limitations that increase the oxygen (O2) cost of breathing impact dyspnea on exertion (DOE) and peak exercise capacity in patients with HFpEF and obesity. As per investigator's hypothesis, obesity is likely a significant contributor to DOE and exercise intolerance in patients with HFpEF.

Heart Failure With Preserved Ejection FractionObesity

University of Texas Southwestern Medical Center78 participantsStarted Jul 2023

Dallas, Texas, United States

TERMINATEDPhase 1< 1 mile

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

NCT04951609

The purpose of this study is to assess the safety and tolerability of Seltorexant as adjunctive therapy to an antidepressant in adolescents with major depressive disorder (MDD) in the short-term compared with placebo.

Depressive Disorder, Major

Janssen Research & Development, LLC31 participantsStarted Sep 2021

Phoenix, Arizona, United States • Anaheim, California, United States • San Diego, California, United States +20 more locations

Targeting Breathing Limitations to Improve Functional Outcomes in HFpEF

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy

Find Trials by Condition in Dallas

A Study of the Relationship of Psychosocial Function With Mood Symptoms in Offspring of Parents With Bipolar Disorder

The Celljuvant Study: A Phase 3 Immunogenicity and Safety Study of aQIVc Vaccine in Adults Aged 50 Years and Older

A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant

A Study of Insulin Efsitora Alfa (LY3209590) as a Weekly Basal Insulin Compared to Insulin Glargine in Adult Participants With Type 2 Diabetes on Multiple Daily Injections

A Study of Esketamine Nasal Spray, Administered as Monotherapy, in Adult Participants With Treatment-resistant Depression

CLN-418 Study on Subjects With Advanced Solid Tumors

A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 to <18 Years) With Type 2 Diabetes Mellitus

A Study of Ustekinumab in Pediatric Participants (U-POPS) With Juvenile Psoriatic Arthritis or Psoriasis

A Study of Seltorexant in Participants With Probable Alzheimer's Disease

Linking Endotypes and Outcomes in Pediatric Acute Respiratory Distress Syndrome

Visualization of the STN and GPi for DBS

Burn Validation Study

A Study to Assess the Bioequivalence of Ustekinumab by Two Different Injection Devices in Healthy Participants

Open-Label Extension: Tolerability and Effects of ALK-001 on Stargardt Disease (TEASE)

User Acceptability Evaluation of Pseudophakic Patients Previously Implanted With the TECNIS Odyssey IOL

Pulmonary Hemodynamics During Exercise - Research Network

Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor

A Study of JNJ-73763989 + Nucleos(t)Ide Analog in Participants Co-Infected With Hepatitis B and Hepatitis D Virus