Clinical Trials in Colorado

Showing 7661-7680 of 18,143 trials

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

NCT03995212

This is a multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety and efficacy of twice-daily (BID) oral CR845 1.0 mg in patients with PBC with moderate-to-severe pruritus. The study includes a 16-week Treatment Period.

Cholestatic Pruritus

Cara Therapeutics, Inc.14 participantsStarted Jun 2019

Coronado, California, United States • Rialto, California, United States • San Francisco, California, United States +11 more locations

COMPLETEDPhase 231 miles

Bendamustine Hydrochloride and Rituximab With or Without Bortezomib Followed by Rituximab With or Without Lenalidomide in Treating Patients With High-Risk Stage II, Stage III, or Stage IV Follicular Lymphoma

NCT01216683

RATIONALE: Drugs used in chemotherapy, such as bendamustine hydrochloride, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as rituximab, can block cancer growth in different ways. Some block the ability of cancer cells to grow and spread. Others find cancer cells and help kill them or carry cancer-killing substances to them. Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Biological therapies, such as lenalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. It is not yet known whether giving bendamustine hydrochloride and rituximab together alone is more effective than giving bendamustine hydrochloride and rituximab together with bortezomib or lenalidomide in treating follicular lymphoma. PURPOSE: This randomized phase II trial is studying giving bendamustine hydrochloride and rituximab together with or without bortezomib followed by rituximab with or without lenalidomide to see how well they work in treating patients with high-risk stage II, stage III, or stage IV follicular lymphoma.

Lymphoma

ECOG-ACRIN Cancer Research Group289 participantsStarted Feb 2011

Greenbrae, California, United States • Salinas, California, United States • Stanford, California, United States +224 more locations

Study to Evaluate the Safety and Efficacy of Oral CR845 (Difelikefalin) in Patients With Primary Biliary Cholangitis (PBC) and Moderate-to-Severe Pruritus

Bendamustine Hydrochloride and Rituximab With or Without Bortezomib Followed by Rituximab With or Without Lenalidomide in Treating Patients With High-Risk Stage II, Stage III, or Stage IV Follicular Lymphoma

Find Trials by Condition in Colorado

Sorafenib in Treating Patients With Refractory Non-Small Cell Lung Cancer

Waterjet Ablation Therapy for Endoscopic Resection of Prostate Tissue (WATER)

Phase Ib Study to Determine MTD of AZD1775 Monotherapy in Patients With Locally Advanced or Metastatic Solid Tumours.

PNT2258 for Treatment of Patients With r/r DLBCL (Wolverine)

Erythropoietin (EPO)+/- Filgrastim (G-CSF) vs. Supportive Therapy Alone for Patients With Myelodysplastic Syndromes

Bedside Resources to Gauge Intravascular Volume Status

Study to Evaluate the Safety, Tolerability, and Efficacy of BGE-175 in Hospitalized Adults With Coronavirus Disease 2019 (COVID-19) That Are Not in Respiratory Failure

Cetuximab, Cisplatin, Fluorouracil, and Radiation Therapy in Treating Patients With Anal Cancer

Canadian-American Spinal Cord Perfusion Pressure and Biomarker Study

A Study to Evaluate the Safety of STS101 in the Acute Treatment of Migraine

Trial of a Chikungunya Vaccine, PXVX0317 CHIKV-VLP, in Healthy Adults

MP1032 Treatment in Patients With Moderate to Severe COVID-19

A Phase 2b Study to Evaluate RIST4721 in Palmoplantar Pustulosis (PPP)

Cyclosporine in Treating Patients With Recurrent or Refractory Angioimmunoblastic T-Cell Lymphoma

PNT2258 for Treatment of Patients With Richter's Transformation (Brighton)

Metvix PDT Versus Vehicle PDT With Aktilite CL128 Lamp in Patients With Actinic Keratosis on the Face and Scalp

Axitinib Given on an Individualized Schedule for Metastatic Renal Cell Cancer

Study of Verinurad in Heart Failure With Preserved Ejection Fraction