Clinical Trials in Cleveland

Showing 8241-8260 of 15,050 trials

Comparing the Efficacy of Epidural and Quadratus Lumborum Analgesia After Open Nephrectomy Surgery

NCT03110081

This study aims to assess if Quadratus Lumborum (QL) blocks are non-inferior to epidural analgesia for pain control and opioid consumption through the third postoperative day in patients having open partial nephrectomy. Patients satisfying all inclusion and exclusion criteria will be randomized in a 1:1 ratio to either epidural catheter or QL catheter.

Open Nephrectomy Surgery

The Cleveland Clinic57 participantsStarted May 2018

Cleveland, Ohio, United States

COMPLETEDPhase 3< 1 mile

Doxorubicin and Cyclophosphamide Plus Paclitaxel With or Without Trastuzumab in Treating Women With Node-Positive Breast Cancer That Overexpresses HER2

NCT00004067

RATIONALE: Drugs used in chemotherapy, such as doxorubicin, cyclophosphamide, and paclitaxel, use different ways to stop tumor cells from dividing so they stop growing or die. Monoclonal antibodies such as trastuzumab can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells. It is not yet known whether combination chemotherapy plus trastuzumab is more effective than combination chemotherapy alone for treating breast cancer. PURPOSE: This randomized phase III trial is studying how well giving combination chemotherapy together with trastuzumab works compared to combination chemotherapy alone in treating women with node-positive stage II or stage IIIA breast cancer that overexpresses HER2.

Breast Cancer

NSABP Foundation Inc2,130 participantsStarted Feb 2000

Huntsville, Alabama, United States • Anchorage, Alaska, United States • Phoenix, Arizona, United States +146 more locations

Comparing the Efficacy of Epidural and Quadratus Lumborum Analgesia After Open Nephrectomy Surgery

Doxorubicin and Cyclophosphamide Plus Paclitaxel With or Without Trastuzumab in Treating Women With Node-Positive Breast Cancer That Overexpresses HER2

Find Trials by Condition in Cleveland

Electromagnetic Tracking of Devices During Interventional Procedures - A Cryoablation Study

SOFI: A Quality Improvement Project to Standardize Use of Intravenous Fluids in Hospitalized Pediatric Patients

Clinical Validation of the Molecular-Based GenePOC Carba Assay for the Detection and Differentiation of Carbapenemase Genes in Rectal Swab Samples.

Study Investigating the Efficacy of Crenolanib With Chemotherapy vs Chemotherapy Alone in R/R FLT3 Mutated AML

Enhanced Protein-Energy Provision Via the Enteral Route in Critically Ill Patients

Heart Sounds Registry

Age of Blood in Children in Pediatric Intensive Care Units

Safety and Efficacy of Corneal Collagen Cross-Linking in Eyes With Keratoconus

Tack Optimized Balloon Angioplasty Study of the Tack Endovascular System™ in Femoropoliteal Arteries

Post Approval Study of the remedē System

Global Anticoagulant Registry in the Field

Comparison of Pre- and Post-discharge Initiation of LCZ696 Therapy in HFrEF Patients After an Acute Decompensation Event

Corneal Collagen Cross-Linking for Ectasia (CXL)

Safety and Efficacy of Corneal Collagen Cross-linking Following LASIK for Treatment of Hyperopia and Hyperopic Astigmatism

BOTOX® (onabotulinumtoxinA) Treatment of Masseter Muscle Prominence

Safety and Tolerability Study of NBI-98854 for the Treatment of Subjects With Tourette Syndrome

Evaluation of TRC101 in Subjects With Metabolic Acidosis Associated With Chronic Kidney Disease

A Study Comparing MB02 and Avastin® in Subjects With Stage IIIB/IV Non-Squamous Non-Small Cell Lung Cancer (NSCLC)